Recurrence patterns of bladder transitional cell carcinoma after radical cystectomy
Bohyun Kim1, Hyuck Jae Choi, Mi-Hyun Kim
1Department of Radiology, Asan Medical Center, University of Ulsan, Seoul, Korea.
Acta Radiologica (Stockholm, Sweden : 1987)
|August 16, 2012
Summary
Bladder cancer recurrence after surgery is common, often appearing at the operation site or lymph nodes. Advanced T stage and lymph node metastasis are key indicators of recurrence risk.
Area of Science:
- Oncology
- Radiology
- Urology
Background:
- Multidetector computed tomography (MDCT) is a key imaging tool for monitoring bladder cancer recurrence post-radical cystectomy.
- Understanding bladder cancer recurrence patterns on CT enhances diagnostic accuracy.
Purpose of the Study:
- To evaluate recurrence patterns of transitional cell carcinoma of the bladder.
- To identify factors associated with bladder cancer recurrence.
Main Methods:
- Retrospective analysis of 149 patients who underwent contrast-enhanced CT and radical cystectomy.
- Radiologists assessed recurrence presence, site, and timing.
- Logistic regression and Kaplan-Meier statistics analyzed associations between recurrence and tumor factors (T stage, lymph node metastasis, grade, diameter).
Main Results:
- Tumor recurrence occurred in 40.3% of patients (60/149) at a mean of 14 months post-surgery.
- Common recurrence sites included the operation site (20), lymph nodes (20), bone (11), and liver (6).
- Advanced T stage (P=0.002) and lymph node metastasis (P<0.001) were significantly associated with recurrence.
Conclusions:
- Transitional cell carcinoma of the bladder frequently recurs at the operation site and lymph nodes.
- T stage and lymph node metastasis are significant predictors of bladder cancer recurrence.
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