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Related Experiment Video

Updated: May 19, 2026

Irradiator Commissioning and Dosimetry for Assessment of LQ α and β Parameters, Radiation Dosing Schema, and in vivo Dose Deposition

Irradiator Commissioning and Dosimetry for Assessment of LQ α and β Parameters, Radiation Dosing Schema, and in vivo Dose Deposition

Published on: March 11, 2021

EchoSeed Model 6733 Iodine-125 brachytherapy source: improved dosimetric characterization using the MCNP5 Monte Carlo

M A Mosleh-Shirazi¹, K Hadad, R Faghihi

¹Center for Research in Medical Physics and Biomedical Engineering and Physics Unit, Radiotherapy Department, Shiraz University of Medical Sciences, Shiraz 71936-13311, Iran. mosleh_amin@hotmail.com

Medical Physics

|August 17, 2012

Summary

This summary is machine-generated.

This study precisely characterized the EchoSeed (125)I brachytherapy source using MCNP5 Monte Carlo simulations. Results offer improved dosimetric data for clinical applications, comparing code accuracy.

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Published on: May 9, 2014

Area of Science:

Medical Physics
Radiation Oncology
Nuclear Medicine

Background:

Brachytherapy seed dosimetry is crucial for accurate radiation delivery.
Previous dosimetric studies of the EchoSeed (125)I source may lack current precision.
Monte Carlo simulations are essential for detailed dosimetric analysis.

Purpose of the Study:

To precisely determine the dosimetric characteristics of the Model 6733 (125)I seed (EchoSeed).
To compare simulation results from MCNP5, MCNP4c2, and PTRAN Monte Carlo codes.
To provide updated, clinically applicable dosimetric data based on the AAPM TG-43 protocol.

Main Methods:

Utilized MCNP5 Monte Carlo code with updated data for enhanced accuracy.
Simulated the EchoSeed geometry and (125)I spectrum in liquid water.
Performed dosimetric characterization according to the AAPM TG-43 updated protocol.

Main Results:

MCNP5 simulations yielded a dose rate constant of 0.965 cGyh⁻¹U⁻¹ (±1.68%).
MCNP5-derived radial dose and anisotropy functions showed closer agreement with measured data (within ±4%) compared to other codes.
Discrepancies between code results were observed, particularly for the dose rate constant.

Conclusions:

MCNP5 provides more accurate dosimetric characterization of the EchoSeed (125)I source.
Updated cross-section libraries in MCNP5 contribute to improved simulation precision.
The derived dosimetric data are suitable for clinical implementation in brachytherapy.