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MRS Shimming: An Important Point Which Should not be Ignored.

B Zeinali-Rafsanjani1,2, R Faghihi1,3, M A Mosleh-Shirazi2,4

  • 1Department of Nuclear Engineering, School of Mechanical Engineering, Shiraz University, Shiraz, Iran.

Journal of Biomedical Physics & Engineering
|October 16, 2018
PubMed
Summary
This summary is machine-generated.

Quality control (QC) is crucial for accurate magnetic resonance spectroscopy (MRS) quantification. Periodic phantom testing ensures shimming effectiveness and reliable metabolic analysis, preventing diagnostic errors.

Keywords:
Quality assuranceQuality controlShimmingMagnetic resonance spectroscopy

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Area of Science:

  • Medical Imaging
  • Spectroscopy
  • Quality Control

Background:

  • Proton magnetic resonance spectroscopy (MRS) analyzes biological fluids metabolically.
  • Accurate MRS requires a homogeneous magnetic field, achieved through shimming.
  • Magnetic field homogeneity is vital for well-defined peaks and uniform water suppression.

Purpose of the Study:

  • To emphasize the importance of shimming in MRS.
  • To highlight the critical role of quality control (QC) in accurate MRS quantification.
  • To assess the performance of an MRS system using a custom-designed phantom.

Main Methods:

  • A cylindrical acrylic phantom, mimicking brain MRS phantoms, was used for a 1.5 T Siemens MRI system.
  • The signals of key metabolites (NAA, Cho, Cr) and distilled water were evaluated.
  • QC tests were conducted using both a Siemens QC phantom and a standard test phantom.

Main Results:

  • The home-made phantom's spectrum significantly differed from the expected spectrum.
  • A systemic issue affected all metabolite signals and even pure distilled water.
  • The MRS system failed QC tests, exhibiting common peak broadening and failing to produce a standard test phantom spectrum.

Conclusions:

  • Simple water peak analysis reveals shimming status and impacts spectral accuracy.
  • Automatic or manual shimming alone does not guarantee spectral accuracy.
  • Periodic QC testing by specialists using test phantoms is essential for reliable MRS.