VIP17/MAL expression modulates epithelial cyst formation and ciliogenesis.

Vinita Takiar1, Kavita Mistry, Monica Carmosino

  • 1Department of Cellular and Molecular Physiology, Yale School of Medicine, New Haven, Connecticut 06520-8026, USA.

Summary

Vesicle integral protein of 17 kDa (VIP17/MAL) overexpression causes abnormal kidney cyst and primary cilium development. This suggests VIP17/MAL may drive renal cystogenesis through ciliary defects.

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