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1Neurologische Klinik, Medizinische Fakultät der Heinrich-Heine-Universität Düsseldorf, Moorenstrasse 5, Düsseldorf. Gabriele.Arendt@uniduesseldorf.de
Fortschritte Der Neurologie-Psychiatrie
|August 17, 2012
Summary
Combination antiretroviral therapy (cART) initially reduced HIV-related neurological issues. However, directly virus-associated nervous system complications are now increasing in HIV patients, requiring updated diagnostic and therapeutic strategies.
Area of Science:
- Neurology
- Infectious Diseases
- Virology
Context:
- The advent of combination antiretroviral therapy (cART) in 1996 led to an expected decline in HIV-associated neurological complications.
- A resurgence in the prevalence and incidence of directly virus-associated neurological conditions in HIV-infected individuals has been observed since the early 2000s.
Purpose:
- To outline practical diagnostic procedures for HIV-associated neurological disorders.
- To present current therapeutic options for these conditions, aligning with German Neurological Society guidelines.
Summary:
- Neurological manifestations in HIV patients include HIV-associated dementia (HAD), myelopathy, polyneuropathies, myopathies, opportunistic infections, and immune reconstitution inflammatory syndrome (IRIS).
- This article details diagnostic approaches and treatment strategies for neurologists managing HIV-infected patients with these complex conditions.
Impact:
- Provides clinicians with updated guidelines for diagnosing and managing a spectrum of HIV-related neurological diseases.
- Aims to improve patient outcomes by addressing the rising incidence of neurological complications in the cART era.
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