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Koi herpesvirus encodes and expresses a functional interleukin-10

Agus Sunarto1, Clifford Liongue, Kenneth A McColl

  • 1CSIRO Livestock Industries, Australian Animal Health Laboratory, Geelong, Victoria, Australia.

Journal of Virology
|August 17, 2012
PubMed
Summary

Koi herpesvirus (KHV) encodes a functional interleukin-10 (IL-10) homolog (khvIL-10) that influences immune responses in fish. This viral IL-10 utilizes the host IL-10 receptor, despite significant structural divergence from host IL-10s.

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