Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Drug Dosing: Geriatric Patients

Drug Dosing: Geriatric Patients

Elderly individuals encompass a diverse population with varying degrees of age-related physiological changes. Defining the elderly presents challenges, as the geriatric population is often arbitrarily categorized as individuals older than 65. However, many individuals in this group lead active and healthy lives, with an increasing number surpassing 85 years and falling into the older elderly category. Physiological changes associated with aging impact performance capacity and homeostatic...

Drug Toxicity: Risk factors

Drug Toxicity: Risk factors

Adverse Drug Reactions (ADRs) are potential complications that arise during pharmacotherapy, influenced by multiple risk factors. Age plays a significant role; both neonates and the elderly are at heightened risk due to their respective immature and diminished metabolic and elimination processes. Gender also impacts ADRs, with females experiencing a 1.5 to 1.7-fold greater risk than males, which may be linked to pharmacokinetic, pharmacodynamic, and hormonal differences. Notably, neonates, the...

Pharmacodynamics in Geriatric Patients: Effects of Age

Pharmacodynamics in Geriatric Patients: Effects of Age

Age-related pharmacokinetic changes are extensively documented, but understanding age-related pharmacodynamic alterations is relatively limited. This knowledge gap can be partly attributed to the complexity of developing appropriate measures of drug responses compared to bioanalytical methods for determining drug concentrations.Most information regarding age-related differences in human pharmacodynamics originates from cross-sectional studies. However, these studies assume that observed mean...

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Distribution

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Distribution

Drug distribution in the human body is influenced by several factors, including plasma protein concentration, body composition, blood flow, tissue-protein concentration, and tissue fluid pH. Among these, changes in plasma protein concentration and body composition due to aging significantly affect how drugs are distributed within the body. Specifically, aging is associated with a decrease in albumin levels by about 10% and an increase in α1-acid glycoprotein levels. These alterations are not...

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Excretion

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Excretion

In geriatric patients, renal physiology undergoes significant changes, including diminished renal blood flow and a lower glomerular filtration rate (GFR), leading to alterations in medication clearance. Drugs such as aminoglycoside antibiotics, lithium, and digoxin, which rely on glomerular filtration for removal from the body, particularly impact pharmacokinetics. These drugs tend to have slower clearance rates in older adults, necessitating careful dosage considerations.Evaluation of renal...

Psychological and Sociocultural Causes of Schizophrenia

Psychological and Sociocultural Causes of Schizophrenia

Schizophrenia, a complex psychiatric disorder, has been historically misunderstood. Early psychological theories attributed its origins to childhood trauma and unresponsive parenting. However, contemporary research largely rejects these notions, favoring the vulnerability-stress hypothesis. This model proposes that individuals with a genetic predisposition to schizophrenia may develop the disorder following exposure to significant environmental stressors. Notably, studies on high-risk...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same journal

ERRATUM.

Ciencia & saude coletiva·2026

Same journal

Digital innovation in the regulation of specialized consultations and exams in Manaus, Brazil: challenges and impacts.

Ciencia & saude coletiva·2026

Same journal

Implementation of eConsults in the Brazilian Unified Health System: proposal of an evaluative model.

Ciencia & saude coletiva·2026

Same journal

Primary Health Care teams and facilities map: a tool for planning and management.

Ciencia & saude coletiva·2026

Same journal

Teleconsultation in primary care: conceptual model and implementation in favela territories.

Ciencia & saude coletiva·2026

Same journal

Electronic system for clinical information management for dental schools: digital integration of teaching and service.

Ciencia & saude coletiva·2026

Search research articles

Related Experiment Video

Updated: May 19, 2026

Assessment of Dependence in Activities of Daily Living Among Older Patients in an Acute Care Unit

Assessment of Dependence in Activities of Daily Living Among Older Patients in an Acute Care Unit

Published on: September 30, 2020

[Suicide risk factors among the elderly].

Sergio Andrés Pérez Barrero¹

¹Sección de Suicidiologia, Sociedad Cubana de Psiquiatría, Bayamo, Granma, Cuba. serper.grm@infomed.sld.cu

Ciencia & Saude Coletiva

|August 18, 2012

Summary

Elderly suicide risk is influenced by depression, abuse, and medical, psychological, and social factors. A practical guide helps evaluate these risks in older adults.

Area of Science:

Gerontology
Psychiatry
Public Health

Context:

Older adults face unique suicide risks.
Identifying and mitigating these risks is crucial for public health.
Existing literature highlights various contributing factors.

Purpose:

To provide an overview of suicide risk factors in the elderly.
To offer a practical guide for assessing suicide risk in this population.

Summary:

Key risk factors include depression, elder abuse, and medical, psychological, and social determinants.
The overview synthesizes current knowledge on geriatric suicide.
A concluding section presents a guide for risk evaluation.

Impact:

More Related Videos

Identifying Frailty Using Point-of-Care Ultrasonography: Image Acquisition and Assessment

Identifying Frailty Using Point-of-Care Ultrasonography: Image Acquisition and Assessment

Published on: July 26, 2024

Related Experiment Videos

Last Updated: May 19, 2026

Assessment of Dependence in Activities of Daily Living Among Older Patients in an Acute Care Unit

Assessment of Dependence in Activities of Daily Living Among Older Patients in an Acute Care Unit

Published on: September 30, 2020

Identifying Frailty Using Point-of-Care Ultrasonography: Image Acquisition and Assessment

Identifying Frailty Using Point-of-Care Ultrasonography: Image Acquisition and Assessment

Published on: July 26, 2024

Aims to improve the identification and management of suicide risk in older adults.
Provides healthcare professionals with tools for risk assessment.
Contributes to suicide prevention strategies for the geriatric population.