Related Experiment Video
Updated: May 19, 2026

Local Anesthetic Thoracoscopy for Undiagnosed Pleural Effusion
Published on: November 10, 2023
Pleural effusion - An unusual cause
Vinoth Ponnurangam Nagarajan1, Anitha Palaniyadi, Muthamilselvan Sathyamoorthi
1Sri Ramachandra Medical College & Research Institute, Chennai, Tamil Nadu, India.
Insights
Hepatitis A infection in children can rarely cause pleural effusion and ascites. These rare extrahepatic complications typically resolve with symptomatic treatment alongside the hepatitis A virus (HAV) infection.
Area of Science:
- Hepatology
- Pediatrics
- Infectious Diseases
Background:
- Hepatitis A virus (HAV) infection is a prevalent cause of hepatitis in children, particularly in developing nations.
- HAV infection is typically self-limiting, with extrahepatic complications being uncommon.
Observation:
- This report details two pediatric cases of Hepatitis A presenting with concurrent pleural effusion and ascites.
- These extrahepatic manifestations were observed alongside the primary HAV infection.
Findings:
- Both pleural effusion and ascites in these patients resolved completely.
- Resolution of the extrahepatic symptoms correlated with the resolution of the Hepatitis A infection following symptomatic treatment.
Implications:
- Healthcare providers, especially pediatricians in developing countries, should recognize the potential for rare extrahepatic manifestations of HAV infection.
- Awareness of these uncommon but reversible complications can prevent unnecessary diagnostic procedures and guide appropriate patient management.
Abstract:
Hepatitis A (HAV) infection is one of the most common forms of hepatitis in the paediatric age group in developing countries. It is usually self-limiting and rarely accompanied by extra hepatic complication. In this article, we report two children with hepatitis A who had associated issues of pleural effusion and ascites. Both issues improved with resolution of hepatitis after symptomatic treatment. Although uncommon, extra hepatic manifestations can occur with hepatitis A. However, they resolve completely. Paediatricians in developing countries should be aware of this rare association to avoid unnecessary investigations.
Related Concept Videos
Pleural Effusion I: Introduction
There are two main types of pleural effusion: transudative and exudative. They are differentiated using Light's criteria,...
Pleural Effusion II: Symptoms and Management
A pleural effusion is the abnormal collection of fluid between the parietal and visceral pleura layers of tissue that form the lining of the lungs and chest cavity. It can occur independently or due to surrounding parenchymal diseases, such as infection, malignancy, or inflammatory conditions.
Clinical Manifestations:
Pleural Disorders: Types and Brief Description
Pneumothorax-I
Pneumothorax can be even further classified as spontaneous, traumatic, and tension pneumothorax.
Pneumothorax II: Pathophysiology
Pleura of the Lungs
