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Updated: May 19, 2026
07:03
Imaging Denatured Collagen Strands In vivo and Ex vivo via Photo-triggered Hybridization of Caged Collagen Mimetic Peptides
Published on: January 31, 2014
Peroxidasin: tying the collagen-sulfilimine knot
1Division of Molecular Medicine and Genetics, Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA. sjweiss@umich.edu
Nature Chemical Biology
|August 22, 2012
Abstract:
Type IV collagen, a major constituent of basement membranes, contains an unusual intermolecular sulfilimine crosslink whose route of biosynthesis has remained undefined. An oxidative triad consisting of peroxidasin, H(2)O(2) and halide is now shown to drive sulfilimine generation in vivo.
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