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Updated: May 19, 2026

Minimal Invasive Resection of Large Retrosternal Thyroid Goiter
Published on: September 20, 2024
Feasibility and safety of minimal-incision thyroidectomy for Graves' disease: a prospective, single-center study
Giuliano Perigli1, Etleva Qirici, Benedetta Badii
1Department of Medical and Surgical Critical Care, Medical School, University of Florence, Florence, Italy.
Background:
The role of minimally invasive surgery in Graves' disease is still controversial. The aim of this study was to compare the clinical outcomes of patients undergoing minimal-incision thyroidectomy with those undergoing conventional thyroidectomy for Graves' disease.
Methods:
A prospective study was performed on 148 patients undergoing total thyroidectomy. Seventy-one patients underwent minimal-incision thyroidectomy and 77 underwent conventional thyroidectomy. Minimal-incision thyroidectomy was proposed if the thyroid volume was ≤ 50 mL.
Results:
There were no significant differences in the operative time between minimal-incision thyroidectomy and conventional thyroidectomy. The length of skin incision was significantly shorter in the minimal-incision thyroidectomy than that in the conventional thyroidectomy group. The incidence of postoperative complications was similar in the 2 groups. Patients undergoing minimal-incision thyroidectomy experienced significantly less postoperative pain and were more satisfied with the cosmetic result than patients who underwent conventional thyroidectomy.
Conclusions:
Minimal-incision thyroidectomy is a feasible and safe option for the surgical treatment of selected patients with Graves' disease.
Related Concept Videos
Graves' Disease I: Introduction
Graves Disease II: Pathophysiology

