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Related Concept Videos

Changes in Skin Color: Clinical Perspectives01:14

Changes in Skin Color: Clinical Perspectives

The first thing a clinician sees is the skin, so the examination of the skin should be part of any thorough physical examination. Most skin disorders are relatively benign, but a few, including melanomas, can be fatal if untreated. A couple of the more noticeable disorders, albinism and vitiligo, affect the appearance of the skin and its accessory organs.
Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...
Skin Cancer01:30

Skin Cancer

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Nephrotic Syndrome II : Assessment and Medical Management01:26

Nephrotic Syndrome II : Assessment and Medical Management

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Chronic Pancreatitis II: Pathophysiology01:21

Chronic Pancreatitis II: Pathophysiology

Chronic pancreatitis is a progressive and irreversible inflammation of the pancreas, most often caused by long-term alcohol abuse, but it can also be related to ductal obstruction, smoking, or genetic factors.Chronic pancreatitis occurs when the pancreas is repeatedly exposed to harmful agents like alcohol, smoking, ductal obstruction, or genetic predisposition. These factors lead to the release of toxic metabolites and inflammatory cytokines, sustaining chronic inflammation in the pancreatic...
Nephrotic Syndrome I : Introduction01:24

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Clinical Applications of Epidermal Stem Cells

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Related Experiment Video

Updated: May 19, 2026

Establishing a Severe Corneal Inflammation Model in Rats Based on Corneal Epithelium Curettage Combined with Corneal Sutures
04:48

Establishing a Severe Corneal Inflammation Model in Rats Based on Corneal Epithelium Curettage Combined with Corneal Sutures

Published on: November 22, 2024

Lichen planus: an update and review.

Amit Sharma1, Rafał Białynicki-Birula, Robert A Schwartz

  • 1Dermatology and Pediatrics, New Jersey Medical School, 185 South Orange Ave, Newark, NJ 07103-2714, USA. asharma915@gmail.com

Cutis
|August 23, 2012
PubMed
Summary

Lichen planus (LP) is a skin condition affecting children and adults, presenting as itchy purple papules. Treatment with steroids can speed recovery, though post-inflammatory hyperpigmentation may occur.

Related Experiment Videos

Last Updated: May 19, 2026

Establishing a Severe Corneal Inflammation Model in Rats Based on Corneal Epithelium Curettage Combined with Corneal Sutures
04:48

Establishing a Severe Corneal Inflammation Model in Rats Based on Corneal Epithelium Curettage Combined with Corneal Sutures

Published on: November 22, 2024

Area of Science:

  • Dermatology
  • Immunology
  • Pediatrics

Background:

  • Lichen planus (LP) is a papulosquamous eruption affecting skin, scalp, nails, and mucous membranes.
  • While more common in adults, LP is an established pediatric disorder.
  • Classic LP presents as purple, polygonal, pruritic papules with characteristic interface dermatitis on histopathology.

Purpose of the Study:

  • To summarize the key features, pathogenesis, and management of lichen planus, particularly in the pediatric population.
  • To highlight the diagnostic criteria and treatment options for LP.
  • To discuss potential long-term sequelae in children.

Main Methods:

  • Review of existing literature on lichen planus.
  • Analysis of clinical presentations and histopathologic findings.
  • Evaluation of treatment strategies and outcomes.

Main Results:

  • LP pathogenesis involves an imbalance of immunologic cellular reactivity.
  • Topical and/or oral steroids expedite recovery and alleviate symptoms.
  • Postinflammatory hyperpigmentation is a common sequela; cutaneous atrophy and pterygium unguis are rare in pediatric cases.

Conclusions:

  • Lichen planus is a treatable condition with a generally favorable prognosis, especially with prompt steroid therapy.
  • Understanding the immunologic basis of LP aids in management.
  • Long-term monitoring for rare sequelae is important in pediatric patients.