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Ookluc: A Plasmodium berghei Line for Identifying Transmission-blocking Compounds
Published on: July 11, 2025
[Study progress on mefloquine against schistosomes and other helminths]
1National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention, Shanghai 200025, China.
Abstract:
In recent years, antimalarial drug mefloquine, an amino alcohol compound, has been found to exhibit potential effect against schistosomes. The feature of antischistosomal properties of mefloquine is that the drug possesses similar killing effect against various development stages of juvenile and adult schistosomes. This paper summarizes the recent three years' progress in experimental studies of mefloquine against schistosomes and other helminthes.

