Heart failure and mechanical circulatory support

Stephen Andrew Esper1, Kathirvel Subramaniam

  • 1Department of Anesthesiology, Duke University Medical Center, Durham, NC, USA.

Insights

Cardiovascular disease (CVD) is a major global health concern, significantly impacting Europe and the USA. This review focuses on congestive heart failure (HF), exploring its epidemiology, pathophysiology, and therapeutic options for anesthesiologists.

Area of Science:

  • Cardiology and Anesthesiology
  • Public Health and Epidemiology

Background:

  • Cardiovascular disease (CVD) is a leading cause of morbidity and mortality globally, representing a significant disease burden in Europe and the USA.
  • Congestive heart failure (HF) is a prevalent condition requiring increased attention, particularly in perioperative and intensive care settings.

Purpose of the Study:

  • To review the epidemiology, pathophysiology, and current therapies for congestive heart failure (HF).
  • To provide anesthesiologists with an understanding of HF management, including mechanical circulatory support and heart transplantation.

Main Methods:

  • Literature review of cardiovascular disease (CVD) and congestive heart failure (HF) epidemiology and pathophysiology.
  • Analysis of established and emerging therapies for end-stage HF, including mechanical circulatory assistance and heart transplantation.

Main Results:

  • Cardiovascular disease (CVD) affects millions worldwide, with heart failure (HF) being a major component.
  • Mechanical circulatory assistance and heart transplantation are key treatments for end-stage HF, with specific indications and contraindications.

Conclusions:

  • Anesthesiologists increasingly encounter patients with heart failure (HF), necessitating comprehensive knowledge of the condition and its management.
  • Understanding the efficacy, safety, and cost of circulatory support therapies is crucial for optimizing patient care in advanced HF.

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