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Exploring Sequence Space to Identify Binding Sites for Regulatory RNA-Binding Proteins
Published on: August 9, 2019
Technical considerations for functional sequencing assays
1Department of Developmental and Cell Biology, University of California, Irvine, California, USA.
Nature Immunology
|August 23, 2012
Abstract:
Next-generation sequencing technologies need careful design of experiments and evaluation of results to meet field requirements. Here we discuss technical considerations for these high-throughput assays, together with criteria to assess the quality of the results and the necessary validation.
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