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Long-term relationships between cholinergic tone, synchronous bursting and synaptic remodeling

Maya Kaufman1, Michael A Corner, Noam E Ziv

  • 1Department of Physiology and Biophysics and Rappaport Institute, Technion Faculty of Medicine, and Network Biology Research Laboratories, Lorry Lokey Center for Life Sciences and Engineering, Haifa, Israel.

Plos One
|August 23, 2012
PubMed
Summary

Cholinergic systems influence brain plasticity by altering synaptic remodeling and network activity. While elevated cholinergic tone initially suppresses bursting, it can recover, indicating limited control over synchronous activity.

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