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Management of hypertension in the elderly population
Raymond V Oliva1, George L Bakris
1FASN, FASH, The University of Chicago Medicine, 5841 S. Maryland, MC 1027 Rm P-328, Chicago, Illinois 60637, USA.
Insights
Hypertension management in older adults is crucial. The consensus recommends a blood pressure goal of less than 140/90 mmHg for the elderly, with diuretics and calcium antagonists as effective treatments.
Area of Science:
- Gerontology
- Cardiovascular Medicine
- Nephrology
Background:
- Hypertension is prevalent in individuals aged 65 and older, with higher rates in African Americans and women.
- Hypertension control is poorer in those aged 70+ compared to 60-69 year olds.
- Limited trials in the elderly population restrict strong recommendations for goal blood pressure (BP).
Purpose of the Study:
- To review the consensus report on hypertension management in the elderly.
- To examine studies on goal BP and nephropathy progression in older adults.
- To provide evidence-based recommendations for hypertension control in this demographic.
Main Methods:
- Review of the American College of Cardiology/American Heart Association consensus report.
- Analysis of specific studies focusing on goal BP and kidney disease in the elderly.
- Synthesis of evidence to support BP targets and treatment strategies.
Main Results:
- General evidence supports a BP goal of <150/80 mmHg for the elderly.
- Consensus recommends <140/90 mmHg, or <140-145 mmHg if tolerated.
- Data for those over 80 are limited, but <150/80 mmHg is suggested.
Conclusions:
- Diuretics and calcium antagonists are effective single agents for hypertension treatment in the elderly.
- Most elderly patients require multiple medications to achieve BP goals.
- Further research is needed for optimal BP targets in the very elderly (over 80).
Abstract:
Hypertension is common in people aged 65 and older. African Americans and women have a higher prevalence of hypertension than white individuals, and in those aged 70 and older, the hypertension was more poorly controlled than in those aged 60-69. The number of trials available in the elderly population compared with the general population are limited; hence, the database for strong recommendations as to goal blood pressure (BP) are limited. The American College of Cardiology with the American Heart Association has recently published a consensus report of management of hypertension in the elderly population. This review presents an overview of this consensus report and reviews specific studies that provide some novel findings regarding goal BP and progression of nephropathy. In general, the evidence strongly supports a BP goal of less than 150/80 mmHg. The evidence review for the consensus report supports a goal of <150/80 mmHg for the elderly with scant data in those over age 80. However, it was decided to set the goal to less than 140/90 mmHg unless the patient cannot tolerate it and then try for 140-145 mmHg. The data are scant at best for those over age 80 mmHg but some evidence exists for <150/80 mmHg. Diuretics and calcium antagonists are the most efficacious single agents for treatment; however, most patients will require two or more drugs to achieve such goals.
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