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Updated: May 19, 2026
Synthesis of Core-shell Lanthanide-doped Upconversion Nanocrystals for Cellular Applications
Published on: November 10, 2017
Theranostic probe based on lanthanide-doped nanoparticles for simultaneous in vivo dual-modal imaging and
Yong Il Park1, Hyung Min Kim, Jeong Hyun Kim
1World Class University Program of Chemical Convergence for Energy & Environment, Institute of Chemical Processes, School of Chemical and Biological Engineering, Seoul National University, South Korea.
Abstract:
Dual-modal in vivo tumor imaging and photodynamic therapy using hexagonal NaYF(4):Yb,Er/NaGdF(4) core-shell upconverting nanoparticles combined with a photosensitizer, chlorin e6, is reported. Tumors can be clearly observed not only in the upconversion luminescence image but also in the magnetic resonance image. In vivo photodynamic therapy by systemic administration is demonstrated under 980 nm irradiation.
