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Updated: May 19, 2026

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Predicting Amputation using Local Circulating Mononuclear Progenitor Cells in Angioplasty-treated Patients with Critical Limb Ischemia
Published on: September 22, 2020
Mentality and organisational changes are key to developing primary angioplasty
Miodrag C Ostojic1, Nevena D Karanovic
1Serbian Academy of Sciences and Arts, Belgrade, Serbia.
Summary
Serbia
Area of Science:
- Cardiology
- Public Health
Background:
- In 2008, Serbia had low rates of reperfusion therapy for ST-elevation myocardial infarction (STEMI).
- Only 19% of STEMI patients received primary percutaneous coronary intervention (p-PCI).
Purpose of the Study:
- To evaluate the impact of the Stent for Life (SFL) Initiative on STEMI treatment in Serbia.
- To assess trends in p-PCI utilization and timely treatment.
Main Methods:
- Analysis of reperfusion therapy data for STEMI patients in Serbia before and after 2009.
- Tracking the increase in p-PCI procedures, PCI centers, and trained cardiologists.
Main Results:
- A significant increase in p-PCI procedures occurred after 2009, driven by policy changes and infrastructure development.
- Direct communication improved patient transport to cathlabs, increasing from 7.5% to 34.2%.
- Despite increased p-PCI numbers, only 38% of patients received treatment within 120 minutes of diagnosis.
Conclusions:
- The SFL Initiative and supporting measures have boosted p-PCI rates in Serbia.
- Timely STEMI treatment remains a challenge, with a need to improve adherence to the 120-minute treatment window.
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