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Updated: May 19, 2026

08:15
Self-Assembly of Gamma-Modified Peptide Nucleic Acids into Complex Nanostructures in Organic Solvent Mixtures
Published on: June 26, 2020
pH-induced morphology-shifting of DNA-b-poly(propylene oxide) assemblies
Zhiyong Zhao1, Liying Wang, Yu Liu
1Beijing National Laboratory for Molecular Sciences, Institute of Chemistry and Graduate School, Chinese Academy of Sciences, Beijing 100190, China.
Abstract:
The designed DNA sequences can make DNA-b-PPO undergo in situ transition between diblock and triblock upon pH changes, consequently, induce a morphology-shifting from spherical micelles to nanofibers. This process is reversible and the assembled structures have been characterized by CD, TEM and fluorescent experiments.

