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Oscillatory shear stress created by fluid pulsatility versus flexed specimen configurations

Manuel Salinas1, David E Schmidt, Miguel Libera

  • 1a Tissue Engineered Mechanics, Imaging and Materials (TEMIM) Laboratory, Department of Biomedical Engineering , Florida International University , Miami , FL , USA.

Computer Methods in Biomechanics and Biomedical Engineering
|August 28, 2012
PubMed
Summary

Physiologically relevant oscillatory shear stress (OSS) for heart valve tissue engineering (HVTE) is maximized by applying pulsatile flow to stationary specimens. This simplifies dynamic HVTE protocols by eliminating the need for complex specimen movement.

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