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Updated: May 19, 2026

Establishment of Deep Hypothermic Circulatory Arrest in Rats
Published on: December 16, 2022
Cerebral protection for aortic arch surgery: deep hypothermia
Gabriele Di Luozzo1, Randall B Griepp
1Department of Cardiothoracic Surgery, Mount Sinai Medical Center, New York, New York 10029, USA. gabriele.diluozzo@mountsinai.org
Deep hypothermic circulatory arrest and branched graft techniques have advanced aortic arch aneurysm surgery. This study details a total arch replacement method using deep hypothermia and selective cerebral perfusion for improved outcomes.
Area of Science:
- Cardiovascular Surgery
- Thoracic Surgery
- Vascular Surgery
Background:
- Aortic arch aneurysm repair has seen significant technical advancements over the past 20 years.
- Deep hypothermic circulatory arrest (DHCA) is widely adopted for managing aortic arch aneurysms.
- The branched graft technique has been utilized since the late 1990s, enhancing surgical results.
Purpose of the Study:
- To describe a refined technique for total aortic arch replacement.
- To highlight the benefits of deep hypothermia and selective cerebral perfusion in aortic arch surgery.
Main Methods:
- The study details a specific surgical technique for total arch replacement.
- This method involves the use of deep hypothermia.
- Selective cerebral perfusion is employed to protect brain function during the procedure.
Main Results:
- The described branched graft technique has improved surgical outcomes.
- The technique has considerably simplified the treatment of aortic arch aneurysms.
- The approach using deep hypothermia and selective cerebral perfusion is effective.
Conclusions:
- Total arch replacement using deep hypothermia and selective cerebral perfusion is a viable and effective technique.
- The branched graft approach offers improved outcomes and simplification in aortic arch aneurysm surgery.
- Continued evolution of surgical techniques benefits patients with aortic arch aneurysms.
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