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Updated: May 19, 2026

A Sensitive Visual Method for the Detection of Hydrogen Sulfide Producing Bacteria
Published on: June 27, 2022
Fluorescent probes for sensing and imaging biological hydrogen sulfide
Vivian S Lin1, Christopher J Chang
1Departments of Chemistry and Molecular and Cell Biology, University of California, Berkeley, CA 94720, USA.
Abstract:
Hydrogen sulfide (H(2)S) has long been recognized as a toxic molecule in biological systems. However, emerging studies now link controlled fluxes of this reactive sulfur species to cellular regulation and signaling events akin to other small molecule messengers, such as nitric oxide, hydrogen peroxide, and carbon monoxide. Progress in the development of fluorescent small-molecule indicators with high selectivity for hydrogen sulfide offers a promising approach for studying its production, trafficking, and downstream physiological and/or pathological effects.
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