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Updated: May 19, 2026

Method of Studying Palatal Fusion using Static Organ Culture
Published on: September 19, 2015
First-trimester assessment of the fetal palate: a novel application of the Volume NT algorithm
Waldo Sepulveda1, Daniel Cafici, Julie Bartholomew
1The Fetal Medicine Center, Fetal Medicine Interest Group GIMEF, Santiago, Chile. fetalmed@yahoo.com
Abstract:
We describe a new technique that can facilitate the first-trimester examination of the fetal palate using the Volume NT algorithm (Samsung Medison, Seoul, Korea), a program that automatically detects the exact midsagittal plane of the head and is primarily designed for semiautomatic measurement of the nuchal translucency thickness. Three-dimensional (3D) data sets from the fetal face were captured with Volume NT and subsequently reformatted with the Oblique View software to obtain orthogonal views of the primary and secondary palate in coronal and axial planes, respectively. By testing this method in selected 3D data sets obtained retrospectively (n = 12) and prospectively (n = 28), we were able to extract clinically acceptable views of the fetal palate in all cases. This preliminary report shows that with this new 3D automation development, early evaluation of the fetal palate is feasible and reproducible and could be easily incorporated into the first-trimester sonographic protocol once its ability to detect abnormal cases is demonstrated.

