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Lid margins: sensitivity, staining, meibomian gland dysfunction, and symptoms
Blanka Golebiowski1, Katrina Chim, Jennifer So
1School of Optometry and Vision Science, The University of New South Wales, Sydney, New South Wales, Australia.
Summary
Lower eyelids are more sensitive and stained but have less meibomian gland dysfunction than upper lids. Tear osmolarity correlates with lid characteristics, but symptoms did not correlate with lid staining.
Area of Science:
- Ophthalmology
- Ocular Surface Disease
Background:
- Ocular surface sensitivity influences tear secretion and ocular comfort.
- The specific role of eyelid margin sensitivity in ocular surface health is not well understood.
Purpose of the Study:
- To characterize eyelid margin sensitivity and its relationship with staining, meibomian gland dysfunction, tear osmolarity, and symptoms.
- To compare characteristics between lower and upper eyelids.
Main Methods:
- Pilot study of 27 healthy subjects.
- Assessed ocular symptoms, tear osmolarity, lid margin staining, meibomian gland dysfunction, and mechanical lid sensitivity.
Main Results:
- Lower eyelids were more sensitive and stained, with less meibomian gland dysfunction than upper eyelids.
- Tear osmolarity correlated with upper-lid staining and lower-lid sensitivity.
- Lid sensitivity was inversely correlated with lower-lid meibomian gland dysfunction; no symptom-staining association found.
Conclusions:
- Significant clinical differences exist between lower and upper eyelids.
- Demonstrated novel relationships between tear osmolarity and eyelid characteristics, including sensitivity.
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