Related Experiment Video
Updated: May 19, 2026
06:04
Surgical Treatment for Benign Prostatic Hyperplasia: Holmium Laser Enucleation of the Prostate (HoLEP).
Published on: March 6, 2018
Various treatment options for benign prostatic hyperplasia: A current update
Alankar Shrivastava1, Vipin B Gupta
1Research Scholar, Jodhpur National University, Jodhpur, Rajasthan, India.
Journal of Mid-Life Health
|August 28, 2012
Summary
This review updates current medications for benign prostatic hyperplasia (BPH), a common condition affecting men over 40. It covers pharmaceuticals, combination therapies, and herbal remedies, highlighting alpha-blockers as preferred for symptom relief.
Area of Science:
- Urology
- Pharmacology
- Integrative Medicine
Background:
- Benign prostatic hyperplasia (BPH) significantly impacts quality of life and is associated with sexual dysfunction in men over 40.
- Current BPH treatment options require an update to address patient needs effectively.
Purpose of the Study:
- To provide a comprehensive review of available medications for BPH.
- To include information on phytotherapies and Ayurvedic treatments for BPH.
- To discuss recent advancements and surgical interventions for BPH.
Main Methods:
- Literature search of MEDLINE, PubMed, and ScienceDirect using keywords related to BPH and its treatments.
- Inclusion of articles on pharmaceutical drugs, combination therapies, herbal remedies, and surgical procedures.
- Analysis of scientific meeting proceedings for relevant data.
Main Results:
- Alpha-one adrenoreceptor blockers (e.g., tamsulosin, alfuzosin) are preferred for symptom relief.
- Combination therapies show potential but require further investigation for early-stage use.
- Phytotherapies show some improvement but lack robust evidence; TURP and MITs are costly.
Conclusions:
- Alpha-blockers remain the primary choice for symptomatic BPH management.
- Further research is needed to establish the role of combination therapies in initial BPH treatment.
- The efficacy and cost-effectiveness of phytotherapies, TURP, and MITs require careful consideration.
Related Concept Videos
01:20Disorders of the Male Reproductive System
Men's health issues are increasingly recognized as significant, with several conditions posing common threats. Among these, testicular cancer is especially prevalent in younger men, particularly those aged 20 to 35 years. The disease often manifests as a painless mass in the testicles, sometimes accompanied by a sensation of heaviness or a dull ache.
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra. Symptoms...
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra. Symptoms...
01:23Treatment for Pulmonary Arterial Hypertension: Prostacyclin Receptor Agonists
Prostacyclin receptor agonists are a class of therapeutic agents integral to managing pulmonary arterial hypertension (PAH). These drugs operate by mimicking the action of prostaglandin I2, or PGI2, a naturally occurring compound in the body.
These agonists bind to the IPR receptor situated on the plasma membrane of the pulmonary artery smooth muscle cells. This binding triggers a cascade of reactions known as the GS-AC-cAMP-PKA pathway. This pathway results in the relaxation of smooth muscle...
These agonists bind to the IPR receptor situated on the plasma membrane of the pulmonary artery smooth muscle cells. This binding triggers a cascade of reactions known as the GS-AC-cAMP-PKA pathway. This pathway results in the relaxation of smooth muscle...
01:28Treatment for Pulmonary Arterial Hypertension: Phosphodiesterase Inhibitors
Phosphodiesterase 5 (PDE5) inhibitors are potent enzymes that function to hydrolyze cyclic nucleotides to their corresponding 5' monophosphates. Their unique biochemical properties have been applied in treating Pulmonary Arterial Hypertension (PAH).
Among the PDE5 inhibitors, sildenafil (Revatio) stands out as a competitive and selective inhibitor. It operates by elevating cellular levels of cGMP and augmenting signaling through the cGMP-PKG pathway, promoting vasodilation. Upon oral...
Among the PDE5 inhibitors, sildenafil (Revatio) stands out as a competitive and selective inhibitor. It operates by elevating cellular levels of cGMP and augmenting signaling through the cGMP-PKG pathway, promoting vasodilation. Upon oral...
01:30Urinary Tract Calculi III: Medical Management
The diagnosis of renal calculi involves several imaging techniques, including non-contrast CT scans and ultrasound. These methods help visualize kidney stones, assess their size and location, and detect possible obstructions. Additionally, Measuring urine pH is useful for diagnosing specific stone types, such as struvite (alkaline pH) and uric acid stones (acidic pH). Cystine stones are primarily linked to cystinuria, a genetic condition. A urinalysis helps detect blood in the urine (hematuria)...
01:30Urinary Tract Infection III: Diagnostic Studies and Interprofessional Care
A healthcare provider can diagnose a urinary tract infection (UTI) through several methods:Medical History and Symptoms: The provider will take a detailed medical history and ask about symptoms such as frequent urination, burning sensation during urination, and lower abdominal pain.Urinalysis: A clean-catch urine sample is collected in a sterile container and tested for the presence of bacteria, white blood cells (leukocytes), nitrites, blood, and protein. The presence of leukocytes and...
01:18Treatment for Pulmonary Arterial Hypertension: Endothelin Receptor Antagonists
Endothelins (ETs) are potent vasoactive peptides critical in the human body's various physiological and pathological processes. One of the most promising therapeutic strategies for treating pulmonary arterial hypertension (PAH) involves counteracting the effects of these endothelins using a class of drugs known as endothelin receptor antagonists.
ETs are synthesized through a complex sequence of enzymatic steps, primarily involving an enzyme referred to as endothelin-converting enzyme (ECE). Of...
ETs are synthesized through a complex sequence of enzymatic steps, primarily involving an enzyme referred to as endothelin-converting enzyme (ECE). Of...