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Updated: Jul 26, 2026

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Novel Diagnostics in Revision Arthroplasty: Implant Sonication and Multiplex Polymerase Chain Reaction
Published on: December 3, 2017
Implant failure with particulate silicone synovitis (detritic synovitis)
M D Perlman1, A D Schor, M L Gold
1Meadowlands Hospital Medical Center, Secaucus, New Jersey.
Summary
Particulate synovitis, caused by silicone hemi-implants, leads to inflammation of synovial tissues. This condition, also known as silastic detritic synovitis, involves small silastic fragments causing adverse tissue reactions.
Area of Science:
- Orthopedic Surgery
- Biomaterials Science
- Pathology
Background:
- Silicone hemi-implants are utilized in various orthopedic procedures.
- Particulate debris from implants can elicit foreign body reactions.
- Synovitis is a common inflammatory response in joint tissues.
Observation:
- A case of particulate synovitis secondary to a silicone hemi-implant is presented.
- The condition is characterized by inflammation of the synovial tissues.
- Microscopic silastic debris was identified as the causative agent.
Findings:
- The inflammation is directly attributed to small, free-floating silastic particles within the joint.
- Histopathological examination confirms the presence of foreign body material.
- A comprehensive literature review on silastic foreign body synovitis is included.
Implications:
- This case underscores the potential for particulate synovitis following silicone implant procedures.
- Awareness of this complication is important for orthopedic surgeons and pathologists.
- Further research into implant material degradation and inflammatory responses may be warranted.

