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Hypoglycemia, hormones and cytokines in fatal meningococcal septicemia
J A Romijn1, M H Godfried, C Wortel
1Department of Intensive Care, University of Amsterdam, The Netherlands.
Journal of Endocrinological Investigation
|October 1, 1990
Abstract:
A unique case report with sequential measurements of the plasma concentrations of glucoregulatory hormones, interleukin-6 and tumor necrosis factor during development of hypoglycemia in fatal meningococcemia is presented. Hormonal explanations for hypoglycemia like hyperinsulinemia or defective hypoglycemic counter-regulation were excluded. Plasma concentrations of interleukin-6 and tumor necrosis factor were skyhigh. The putative relation between cytokines and hypoglycemia in sepsis is discussed.