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Updated: May 19, 2026

A Mouse Distraction Osteogenesis Model
Published on: November 14, 2018
A novel device for long bone osteodistraction: description of device and case series
Petros Konofaos1, Anil Kashyap, Mike D Neel
1Memphis, Tenn. From the Department of Plastic Surgery, University of Tennessee Health Science Center, and the Department of Surgery, St. Jude Children's Research Hospital.
Abstract:
The purpose of this study was to present a novel intramedullary device (M-Bone; Phenix, Paris, France) that contains a mechanism for internal osteodistraction and bone transport in patients with segmental bone defects or limb length discrepancy after limb salvage operations. A total of five patients with primary bone tumors were enrolled in the study. After implantation, daily lengthening was performed in an outpatient setting either by the patient or with the help of a therapist, without the use of anesthesia. This unique device offers a totally new approach for the treatment of segmental bone defects or limb length discrepancy. It is designed to expand the remaining native bone by a magnetically activated drive system and induces new bone formation using osteodistraction and bone transport.
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