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Allergic fungal rhinosinusitis in chronic rhinosinusitis

S Shrestha1, P Kafle, J Akhter

  • 1Department of ENT, Head and Neck Surgery, Kathmandu Medical College Teaching Hospital, Nepal. sangitadr@yahoo.com

Journal of Nepal Health Research Council
|August 30, 2012
PubMed
Abstract

Insights

Allergic fungal rhinosinusitis is common in chronic rhinosinusitis patients. Diagnosis requires specific tests like fungus culture and IgE to fungal antigens.

Area of Science:

  • Otolaryngology
  • Mycology
  • Immunology

Background:

  • Rhinosinusitis involves inflammation of nasal and sinus mucosa, potentially causing polyps.
  • Chronic rhinosinusitis presents with mucosal changes and symptoms like nasal blockage.

Purpose of the Study:

  • To determine the prevalence of allergic fungal rhinosinusitis (AFRS).
  • To investigate AFRS in patients with chronic rhinosinusitis undergoing functional endoscopic sinus surgery (FESS).

Main Methods:

  • Patients with chronic rhinosinusitis undergoing FESS were studied.
  • Surgical specimens were analyzed using mycology and histopathology for fungal identification.

Main Results:

  • Headache (82%) and nasal block (90%) were the most frequent symptoms.
  • Fungal elements were detected in 16% of cases via KOH and 22% via histopathology.

Conclusions:

  • Allergic fungal rhinosinusitis is a common condition in chronic rhinosinusitis patients.
  • Definitive diagnosis requires specific tests, including fungus culture and IgE/skin testing for fungal antigens.

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