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Related Concept Videos

Attention-Deficit/Hyperactivity Disorder01:30

Attention-Deficit/Hyperactivity Disorder

Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder characterized by persistent inattention, hyperactivity, and impulsivity. It affects approximately 5-8% of children globally, with around 60-70% of cases persisting into adulthood. ADHD has significant implications for educational attainment, social interactions, and occupational success.
Diagnostic Criteria and Symptoms
To diagnose ADHD, symptoms must manifest before age 12 and be evident across multiple settings.
Drug Toxicity: Risk factors01:24

Drug Toxicity: Risk factors

Adverse Drug Reactions (ADRs) are potential complications that arise during pharmacotherapy, influenced by multiple risk factors. Age plays a significant role; both neonates and the elderly are at heightened risk due to their respective immature and diminished metabolic and elimination processes. Gender also impacts ADRs, with females experiencing a 1.5 to 1.7-fold greater risk than males, which may be linked to pharmacokinetic, pharmacodynamic, and hormonal differences. Notably, neonates, the...

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Related Experiment Video

Updated: May 19, 2026

Event Related Potentials (ERPs) and other EEG Based Methods for Extracting Biomarkers of Brain Dysfunction: Examples from Pediatric Attention Deficit/Hyperactivity Disorder (ADHD)
10:02

Event Related Potentials (ERPs) and other EEG Based Methods for Extracting Biomarkers of Brain Dysfunction: Examples from Pediatric Attention Deficit/Hyperactivity Disorder (ADHD)

Published on: March 12, 2020

Reaction time variability in ADHD: a review.

Leanne Tamm1, Megan E Narad, Tanya N Antonini

  • 1Department of Pediatrics-MC10006, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA. leanne.tamm@cchmc.org

Neurotherapeutics : the Journal of the American Society for Experimental Neurotherapeutics
|August 30, 2012
PubMed
Summary
This summary is machine-generated.

Reaction time variability is a key indicator in Attention-Deficit/Hyperactivity Disorder (ADHD) research. Further studies are needed to compare ADHD with other disorders and refine measurement methods for greater accuracy.

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Area of Science:

  • Cognitive Neuroscience
  • Neurodevelopmental Disorders

Background:

  • Intra-individual reaction time variability is a significant focus in Attention-Deficit/Hyperactivity Disorder (ADHD) research.
  • Increased reaction time variability is consistently observed in individuals with ADHD compared to controls.
  • Direct comparisons with other disorders exhibiting heightened reaction time variability are scarce.

Purpose of the Study:

  • To review the existing literature on reaction time variability in ADHD.
  • To explore the impact of various manipulations on reaction time variability.
  • To highlight the need for refined methodologies in assessing reaction time variability.

Main Methods:

  • Literature review of studies on reaction time variability in ADHD.
  • Analysis of research examining behavioral and neurophysiological correlates.
  • Evaluation of the sensitivity of reaction time variability to different experimental manipulations.

Main Results:

  • Stimulus treatment shows consistent reduction in reaction time variability.
  • The effects of motivational incentives and stimulus event rate are less clear.
  • Current interpretations link heightened variability to attentional lapses and task-negative network activity.

Conclusions:

  • More research is required to compare ADHD with other disorders and understand the underlying mechanisms of reaction time variability.
  • Future studies should adopt more precise measures to capture specific components of reaction time variability.
  • Assessment of variability needs to consider cognitive and motivational contexts.