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Published on: April 5, 2016
Evidence that superior colliculi are involved in the control of amygdala-kindled seizures
1Laboratoire de Médecine Expérimentale, INSERM U249, CNRS UPR41, Institut de Biologie, Montpellier, France.
Abstract:
The effects of bilateral high radiofrequency lesions of superior colliculus (SC) were studied on amygdala kindling. The results demonstrate that a selective destruction of the SC only slightly facilitated the development of kindling. However, the most remarkable effect was the increase of afterdischarge and motor seizure duration observed when SC-lesioned animals reached the generalized seizures. These data confirm that the superior colliculi participate in controlling the generalization of kindled seizures.
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