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Endoscopic Bilateral Nipple-sparing Mastectomy via a Single Axillary Incision with Immediate Pre-pectoral Implant-based Breast Reconstruction
Published on: May 17, 2024
[Quo vadis? Breast implants--current trends and new concepts]
I Sukhova1, D Müller, M Eisenmann-Klein
1Klinik und Poliklinik für Plastische Chirurgie und Handchirurgie, Klinikum rechts der Isar, Technische Universität München, München.
Advancements in breast implant technology focus on surface modifications to improve biocompatibility and reduce capsular contracture. New drug-eluting coatings show promise for localized treatment, minimizing side effects.
Area of Science:
- Biomaterials science and regenerative medicine
- Plastic and reconstructive surgery
- Drug delivery systems
Context:
- Breast augmentation and reconstruction frequently utilize implants.
- Capsular contracture remains a significant complication.
- Recent concerns regarding specific implant materials necessitate improved safety and efficacy.
Purpose:
- To review current trends in breast implant surface modifications.
- To explore strategies for enhancing biocompatibility and reducing capsular contracture.
- To discuss novel drug delivery approaches using implant surfaces.
Summary:
- Breast implants have evolved through several generations, with modifications to surface textures and coatings (e.g., polyurethane, titanium).
- Recent research focuses on antifibrotic and antibacterial coatings, biomimicry, and nanotechnology to improve biocompatibility and reduce capsular contracture.
- Drug delivery systems utilizing implant surfaces offer potential for localized, sustained release to manage complications.
Impact:
- Novel coating technologies could enable localized drug administration, potentially reducing systemic side effects.
- Further research is needed to address controlled drug release, long-term outcomes, and safety of continuous local drug administration.
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