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Dynamic Imaging of Chimeric Antigen Receptor T Cells with [18F]Tetrafluoroborate Positron Emission Tomography/Computed Tomography
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Published on: February 17, 2022

Insight into the dynamics, localization and magnitude of antigen-specific immune responses by [(18)F]FLT PET imaging

Erik H J G Aarntzen1, Mangala Srinivas, Cornelius J A Punt

  • 1Department of Tumor Immunology; Radboud University Nijmegen Medical Centre (RUNMC); Nijmegen, The Netherlands ; Department of Medical Oncology; Radboud University Nijmegen Medical Centre (RUNMC); Nijmegen, The Netherlands.

Oncoimmunology
|August 31, 2012
PubMed

In order for cellular therapeutics to succeed, comprehensive monitoring of the transplanted cells in vivo is required i.e., their localization, functionality and numbers in a longitudinal manner. Recently, dendritic cell based vaccines have been monitored by their effect on lymphocyte activation using [(18)F]FLT PET in cancer patients.

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