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Updated: May 19, 2026

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Preparation of Tumor Antigen-loaded Mature Dendritic Cells for Immunotherapy
Published on: August 1, 2013
Tumor conditioned media from colorectal cancer patients inhibits dendritic cell maturation
Adriana J Michielsen1, Jacintha N O'Sullivan, Elizabeth J Ryan
1Department of Surgery; Trinity Centre for Health Sciences; Institute of Molecular Medicine; St. James's Hospital; Dublin, Ireland.
Oncoimmunology
|August 31, 2012
Abstract:
Tumors inhibit dendritic cell maturation and function in order to evade host immunity. We showed that conditioned media from tumor explant tissue, taken from metastatic colorectal cancer patients, significantly inhibits maturation of dendritic cells.
