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Fabricating Highly Open Porous Microspheres (HOPMs) via Microfluidic Technology
Published on: May 16, 2022
Recent patent in controlled porosity osmotic pump
Alpesh Patel1, Tarak Mehta, Mukesh Patel
1Department of Pharmaceutical Technology, Shri B. M. Shah College of Pharmaceutical Education and Research, Modasa, Gujarat, India. alpesh301085@gmail.com
Recent Patents on Drug Delivery & Formulation
|September 1, 2012
Summary
This study reviews patents for porous osmotic pumps, a drug delivery system providing 24-hour controlled release. These pumps create micropores in situ and are unaffected by physiological factors, enhancing drug delivery applications.
Area of Science:
- Pharmaceutical Sciences
- Biomaterials Engineering
- Drug Delivery Systems
Background:
- Controlled drug release is crucial for therapeutic efficacy and patient compliance.
- Osmotic pump systems offer a reliable method for sustained drug delivery.
- Existing osmotic pumps may be influenced by physiological variations, impacting drug release profiles.
Purpose of the Study:
- To conduct a patent study on porous osmotic pump drug delivery systems.
- To analyze the technology behind in situ micropore formation in osmotic pumps.
- To evaluate the independence of porous osmotic pump performance from physiological factors.
Main Methods:
- Comprehensive review of patents related to porous osmotic pump technology.
- Analysis of the composition and mechanism of pore-forming additives in coating membranes.
- Assessment of studies demonstrating the robustness of the delivery system across different physiological conditions.
Main Results:
- Porous osmotic pumps utilize water-soluble additives to form micropores upon hydration, enabling controlled drug release.
- These systems provide a consistent 24-hour drug release profile.
- Drug delivery performance is demonstrated to be independent of various physiological factors.
Conclusions:
- Porous osmotic pump technology offers a robust and reliable platform for controlled drug delivery.
- The in situ micropore formation mechanism ensures consistent drug release, overcoming limitations of previous systems.
- This patent review highlights the potential of porous osmotic pumps for advanced pharmaceutical applications.
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