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Principles and procedures in forensic toxicology.
1Toxicology Department, Cuyahoga County Region Forensic Science Laboratory, Cuyahoga County Medical Examiner's Office, 11001 Cedar Avenue, Cleveland, OH 44106, USA. jfwyman@cuyahogacounty.us
This review details modern forensic toxicology lab procedures, covering behavioral and postmortem toxicology. It emphasizes quality assurance, specimen selection, and interpreting results considering factors like drug interactions and decomposition.
Area of Science:
- Forensic Toxicology
- Analytical Chemistry
- Pathology
Background:
- Modern forensic toxicology laboratories operate under strict principles and procedures.
- Behavioral and postmortem toxicology are critical sub-disciplines within forensic science.
Purpose of the Study:
- To provide a comprehensive review of the principles and procedures in a modern forensic toxicology laboratory.
- To discuss key aspects of behavioral and postmortem toxicology relevant to laboratory practice and interpretation.
Main Methods:
- Review of established principles and procedures in forensic toxicology.
- Discussion of laboratory accreditation, analyst certification, and chain of custody.
- Examination of testing services, specimen selection, and quality assurance.
Main Results:
- Detailed explanation of operational aspects including analyst certification and lab accreditation.
- Outlined typical testing services, rationale for specimen selection, and quality assurance principles.
- Highlighted factors crucial for interpreting postmortem toxicology results, such as drug interactions, redistribution, and decomposition effects.
Conclusions:
- Effective forensic toxicology relies on robust procedures, quality assurance, and meticulous interpretation.
- Accurate toxicological analysis and interpretation are vital for legal and clinical outcomes.
- Understanding postmortem specific factors is essential for accurate interpretation of toxicology data.
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