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Local Anesthetics: Differential Sensitivity of Nerve Fibers

Local Anesthetics: Differential Sensitivity of Nerve Fibers

Local anesthetics (LAs) block the sodium channels of nerve trunks, sensory nerve endings, and neuromuscular junctions. Although LAs can block all kinds of nerves, the sensitivity of nerve fibers differs according to nerve types and structures. LAs are known to block myelinated fibers faster than unmyelinated ones. Also, they block pain or sensory neurons at low concentrations without affecting the motor neurons involved in muscle contractions. This helps relieve labor pain without affecting the...

Local Anesthetics: Adverse Effects

Local Anesthetics: Adverse Effects

While local anesthetics are generally safe and well-tolerated, they can occasionally cause adverse effects that vary in severity. Local anesthetics can induce toxicity at two distinct levels. They can either produce local effects through direct contact with the neural elements or be absorbed into the bloodstream from the injection site, leading to systemic effects.
Once absorbed into the systemic circulation, local anesthetics can affect the organs that depend on the functioning of sodium...

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Symptomatic neural loop causing hemidigital anesthesia: case report.

Kurt J Hofmann¹, David E Ruchelsman

¹Department of Orthopaedic Surgery, Tufts University School of Medicine, Boston, MA, USA.

The Journal of Hand Surgery

|September 4, 2012

Summary

This summary is machine-generated.

Symptomatic digital neural loops are rare. A case of hemidigital anesthesia caused by a digital nerve loop and artery is presented, with successful surgical resolution.

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Area of Science:

Anatomy
Neurology
Vascular Surgery

Background:

Digital neural loops are anatomical variations often found in cadaveric studies.
Symptomatic presentations of these neural loops are uncommon in clinical practice.

Observation:

A patient presented with hemidigital anesthesia attributed to a proper digital nerve neural loop.
The neural loop was found to be penetrated by its accompanying common digital artery within the palm.

Findings:

Surgical intervention involved neurolysis of the median nerve and digital nerves.
The common digital artery was transected, transposed from the neural loop, and repaired.

Implications:

Successful surgical management led to complete resolution of sensory symptoms within six weeks.
This case highlights the importance of considering neural loop compression in the differential diagnosis of digital anesthesia.