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Published on: May 26, 2023
Ultrasound-guided corticosteroid injection therapy for juvenile idiopathic arthritis: 12-year care experience
Cody M Young1, William E Shiels, Brian D Coley
1Department of Radiology and The Children's Radiological Institute, Nationwide Children's Hospital, 700 Children's Drive, Columbus, OH 43205, USA. cody.young@nationwidechildrens.org
Insights
Ultrasound-guided corticosteroid injections offer precise and safe treatment for juvenile idiopathic arthritis. An age-weight-joint-based protocol enhances care for children with this condition.
Area of Science:
- Pediatric Rheumatology
- Musculoskeletal Imaging
- Interventional Pain Management
Background:
- Intra-articular corticosteroid injections are established treatments for juvenile idiopathic arthritis (JIA).
- Current literature lacks comprehensive data on the scope of ultrasound-guided corticosteroid therapy in pediatric patients.
- A standardized, joint-based corticosteroid dosing protocol for JIA is needed to optimize interdisciplinary care.
Purpose of the Study:
- To detail the spectrum of care, technique, and safety of ultrasound-guided corticosteroid injections in JIA patients.
- To introduce and evaluate an age-weight-joint-based corticosteroid dosing protocol for JIA.
Main Methods:
- Retrospective analysis of 198 JIA patients (21 months to 28 years).
- Ultrasound-guided corticosteroid injections administered to symptomatic joints and tendon sheaths.
- Development and application of an age-weight-joint-based corticosteroid dose protocol.
Main Results:
- 1,444 ultrasound-guided injections performed (1,340 joints, 104 tendon sheaths).
- Injections covered a wide range of appendicular joints and temporomandibular joints.
- Complications occurred in 2.6% of injections, including localized tissue reactions.
Conclusions:
- Ultrasound-guided corticosteroid injections provide dynamic, precise, and safe treatment across the pediatric musculoskeletal system.
- The developed age-weight-joint-based protocol is effective and crucial for integrated JIA patient care.
Background:
Intra-articular corticosteroid injections are a safe and effective treatment for patients with juvenile idiopathic arthritis. The potential scope of care in ultrasound-guided corticosteroid therapy in children and a joint-based corticosteroid dose protocol designed to optimize interdisciplinary care are not found in the current literature.
Objective:
The purpose of this study was to report the spectrum of care, technique and safety of ultrasound-guided corticosteroid injection therapy in patients with juvenile idiopathic arthritis and to propose an age-weight-joint-based corticosteroid dose protocol.
Materials And Methods:
A retrospective analysis was performed of 198 patients (ages 21 months to 28 years) referred for treatment of juvenile idiopathic arthritis with corticosteroid therapy. Symptomatic joints and tendon sheaths were treated as prescribed by the referring rheumatologist. An age-weight-joint-based dose protocol was developed and utilized for corticosteroid dose prescription.
Results:
A total of 1,444 corticosteroid injections (1,340 joints, 104 tendon sheaths) were performed under US guidance. Injection sites included small, medium and large appendicular skeletal joints (upper extremity 497, lower extremity 837) and six temporomandibular joints. For patients with recurrent symptoms, 414 repeat injections were performed, with an average time interval of 17.7 months (range, 0.5-101.5 months) between injections. Complications occurred in 2.6% of injections and included subcutaneous tissue atrophy, skin hypopigmentation, erythema and pruritis.
Conclusion:
US-guided corticosteroid injection therapy provides dynamic, precise and safe treatment of a broad spectrum of joints and tendon sheaths throughout the entire pediatric musculoskeletal system. An age-weight-joint-based corticosteroid dose protocol is effective and integral to interdisciplinary care of patients with juvenile idiopathic arthritis.
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