Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Adrenergic Agonists: Therapeutic Uses01:30

Adrenergic Agonists: Therapeutic Uses

Adrenergic agonists have diverse therapeutic uses across various medical conditions and emergencies.
Emergency and Intensive Care Unit (ICU) applications: Pressor agents increase blood pressure, heart rate, and contractility in shock and organ failure situations. Dopamine can induce vasodilation and stimulate adrenoceptors. Endogenous catecholamines are effective in treating cardiogenic shock. α2-agonists like clonidine can reverse anesthesia-induced hypertension.
Allergies and anaphylaxis:...
Allergic Reactions02:06

Allergic Reactions

Overview
Allergic Reactions: Anaphylaxis01:30

Allergic Reactions: Anaphylaxis

Anaphylaxis is a severe, life-threatening hypersensitivity reaction mediated by Immunoglobulin E (IgE) antibodies. When IgE binds to allergens, it triggers the release of mediators– histamine, leukotrienes, and prostaglandins from mast cells and basophils. These mediators cause vasodilation, edema, and inflammation, leading to various symptoms.The primary allergens causing anaphylaxis include food items (e.g., peanuts, shellfish), drugs (e.g., penicillin, asparaginase, corticotropin, heparin),...
Cardiopulmonary Resuscitation IV: Pharmacological Management01:25

Cardiopulmonary Resuscitation IV: Pharmacological Management

Pharmacologic intervention is crucial in treating cardiac arrest patients during ACLS or Advanced Cardiovascular Life Support. The ACLS algorithms guide the administration of specific drugs based on the patient's cardiac arrest rhythm, which includes pulseless ventricular tachycardia (VT), ventricular fibrillation (VF), asystole, and pulseless electrical activity (PEA).EpinephrineIndication: Epinephrine is the first-line drug for all cardiac arrest rhythms.Mechanism of Action: Epinephrine...
Cardiopulmonary Resuscitation III: AED Use01:23

Cardiopulmonary Resuscitation III: AED Use

Introduction to AEDAn Automated External Defibrillator (AED) is a portable medical device that analyzes the heart's rhythm and, if necessary, delivers an electrical shock to help the heart re-establish an effective rhythm during sudden cardiac arrest (SCA). SCA occurs when the heart suddenly and unexpectedly stops beating, leading to a loss of blood flow to the brain and other vital organs. In such emergencies, time is of the essence, and using an AED, combined with Cardiopulmonary...
Inhaled Medications01:23

Inhaled Medications

Inhaled medications are crucial for managing chronic obstructive pulmonary disease (COPD) and asthma. They are essential for effective treatment and control, ensuring optimal respiratory health and well-being. Inhaled medication delivers drugs directly to the lungs, providing a rapid onset of action and reducing systemic side effects compared to oral or injectable medications. Three primary types of inhalation devices are used to administer these medications: nebulizers, metered-dose inhalers...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Anaphylaxis Clinical Care Pathway: Incorporating Intranasal Epinephrine (Adrenaline).

The journal of allergy and clinical immunology. In practice·2026
Same author

XGBoost (eXtreme Gradient Boosting) Can Predict Organisms Growing in Urine Culture from the Emergency Department.

The western journal of emergency medicine·2026
Same author

Extracorporeal Life Support Use During Severe Anaphylaxis: A Systematic Review and Pooled Analysis of Individual Patient Data.

Journal of cardiothoracic and vascular anesthesia·2026
Same author

Motivating Factors for Participating in the Geriatric Emergency Department Guidelines 2.0.

Academic emergency medicine : official journal of the Society for Academic Emergency Medicine·2026
Same author

Non-injectable versus injectable epinephrine treatment thresholds for acute allergic reactions in the community.

The journal of allergy and clinical immunology. In practice·2026
Same author

Epinephrine and emergency medical services activation recommendations during acute allergic reactions in community settings: International consensus report.

The Journal of allergy and clinical immunology·2025

Related Experiment Video

Updated: May 19, 2026

Sterile Pericarditis in Aachener Minipigs As a Model for Atrial Myopathy and Atrial Fibrillation
08:56

Sterile Pericarditis in Aachener Minipigs As a Model for Atrial Myopathy and Atrial Fibrillation

Published on: September 24, 2021

Epinephrine auto-injector pandemic.

Ronna L Campbell1, Veena Manivannan, Martha F Hartz

  • 1Department of Emergency Medicine, Division of Pediatric Allergy, Immunology, and Pulmonology, Mayo Clinic, Rochester, MN, USA. campbell.ronna@mayo.edu

Pediatric Emergency Care
|September 4, 2012
PubMed
Summary

Anaphylaxis management relies on epinephrine auto-injectors. This article examines rising prescriptions, their causes, proper usage, and handling accidental injections for better patient outcomes.

More Related Videos

Fabrication of Pulsatile Polymeric Microparticles Encapsulating Rabies Antigen
07:44

Fabrication of Pulsatile Polymeric Microparticles Encapsulating Rabies Antigen

Published on: May 12, 2023

Measuring Local Anaphylaxis in Mice
07:49

Measuring Local Anaphylaxis in Mice

Published on: October 14, 2014

Related Experiment Videos

Last Updated: May 19, 2026

Sterile Pericarditis in Aachener Minipigs As a Model for Atrial Myopathy and Atrial Fibrillation
08:56

Sterile Pericarditis in Aachener Minipigs As a Model for Atrial Myopathy and Atrial Fibrillation

Published on: September 24, 2021

Fabrication of Pulsatile Polymeric Microparticles Encapsulating Rabies Antigen
07:44

Fabrication of Pulsatile Polymeric Microparticles Encapsulating Rabies Antigen

Published on: May 12, 2023

Measuring Local Anaphylaxis in Mice
07:49

Measuring Local Anaphylaxis in Mice

Published on: October 14, 2014

Area of Science:

  • Allergy and Immunology
  • Emergency Medicine
  • Pharmacology

Background:

  • Anaphylaxis is a severe allergic reaction requiring immediate treatment.
  • Epinephrine auto-injectors are critical for managing anaphylaxis, especially in non-medical settings.
  • There is a notable increase in epinephrine auto-injector prescriptions.

Purpose of the Study:

  • To provide an overview of the rising trend in epinephrine auto-injector prescriptions.
  • To identify the causes and contributing factors behind increased prescriptions.
  • To review current indications, proper usage, and management of accidental injections.

Main Methods:

  • Literature review of trends in epinephrine auto-injector prescriptions.
  • Analysis of factors contributing to increased prescription rates.
  • Summary of clinical guidelines for indications and use.

Main Results:

  • Epinephrine auto-injector prescriptions are increasing.
  • Multiple factors contribute to this rise, including increased awareness and prevalence of allergies.
  • Guidelines exist for appropriate prescription and use.

Conclusions:

  • The increasing use of epinephrine auto-injectors highlights their importance in anaphylaxis management.
  • Understanding prescription trends and proper usage is vital for healthcare providers and patients.
  • Education on correct auto-injector use and management of side effects is essential.