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Updated: May 19, 2026

An Orthotopic Endometrial Cancer Model with Retroperitoneal Lymphadenopathy Made From In Vivo Propagated and Cultured VX2 Cells
Published on: September 12, 2019
[Old and new staging of endometrial carcinoma]
1Department of Gynecology, Xiaoshan Hospital, Hangzhou 311201, China.
Objective:
To explore the rationality and clinical significance for the old and new surgical-pathological staging in endometrial carcinoma.
Methods:
The clinical profiles and prognostic particulars were analyzed retrospectively in 92 cases of endometrial carcinoma from June 2005 to June 2011 at Xiaoshan Hospital. And the old and new surgical-pathological staging methods were applied to observe their rationality and treatment prognosis.
Results:
There was 72.8% (67/92) for clinical stage I in the old surgical-pathological staging while 7.6% (7/92) for clinical stage II and 19.7% (18/92) for clinical stage III. There was 85.9% (79/92) for clinical stage I in the new surgical-pathological staging, 3.3% (3/92) for clinical stage IIand 10.7% (10/92) for clinical stage III. The detection rate of cancer cell was 8.7% (8/92) in peritoneal fluid. The positive rate of pelvic lymph node was 12.9% (11/85). A period of survival rates were compared among P > 0.05 after 3 years and 5 years of IA, IB and IIA. There was no statistical significance; there were statistical significance between IB and IC periods (P < 0.05). The survival of deep myometrial invasion was significantly shorter than that of superficial muscle layer. The positive rate of abdominal aortic lymph node was 3.8% (1/26). Six patients with positive lymph nodes died postoperatively of cancer within 4 to 28 months.
Conclusion:
The new surgical-pathological staging is more objective, practical, simple and convenient than its old counterpart. Deep myometrial infiltration and positive lymph node are important prognostic factors of endometrial carcinoma. The positive rate of lymph node remains low in early low-risk endometrial carcinoma and routine excision of lymph node is of little significance.

