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In vitro Reconstitution of the Active T. castaneum Telomerase
Published on: July 14, 2011
Total synthesis of laetevirenol A
Young Lok Choi1, Bum Tae Kim, Jung-Nyoung Heo
1Medicinal Chemistry Research Center, Korea Research Institute of Chemical Technology, 141 Gajeong-ro, Daejeon 305-600, Korea.
The Journal of Organic Chemistry
|September 6, 2012
Abstract:
The first complete synthesis of laetevirenol A was performed in nine steps via intramolecular Friedel-Crafts alkylation in a trans-selective manner. The key phenanthrene intermediate was synthesized by a one-pot Suzuki-Miyaura coupling and an aldol condensation cascade reaction.
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