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Related Concept Videos

Sex-linked Disorders01:43

Sex-linked Disorders

Like autosomes, sex chromosomes contain a variety of genes necessary for normal body function. When a mutation in one of these genes results in biological deficits, the disorder is considered sex-linked.
Sexually Transmitted Infections01:26

Sexually Transmitted Infections

Sexually transmitted infections (STIs) are diseases transmitted primarily through unsafe sexual interactions. Bacteria, viruses, or parasites cause them and can result in severe health complications if untreated.ChlamydiaThe bacterium Chlamydia trachomatis is responsible for the disease Chlamydia, the most common STI in the United States. This peculiar pathogen requires human cells to reproduce, residing intracellularly. The initial infection often goes unnoticed because it typically does not...
Multiple Allele Traits01:49

Multiple Allele Traits

The Concept of Multiple Allelism
The Ratio of X Chromosome to Autosomes02:45

The Ratio of X Chromosome to Autosomes

In most organisms, sex is determined by the ratio of X and Y chromosomes. However, in some organisms, such as Drosophila and C.elegans, sex is determined by the ratio of the number of X chromosomes to the number of sets of autosomes. The Y chromosome in Drosophila is active but does not determine sex. It contains genes responsible for the production of sperms in adult flies.  
Normal male Drosophila has a ratio of one X chromosome to two sets of autosomes. In contrast, normal female Drosophila...

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Related Experiment Video

Updated: May 18, 2026

A Human Fallopian Tube Model for Investigation of C. trachomatis Infections
09:11

A Human Fallopian Tube Model for Investigation of C. trachomatis Infections

Published on: August 11, 2012

True hermaphrodite: a case report.

Muhammad Zafar Iqbal1, Mazhar Rafee Jam, Muhammad Saleem

  • 1Department of Paediatric Surgery, Sheikh Zayed Medical College Rahim Yar Khan, Pakistan.

APSP Journal of Case Reports
|September 7, 2012
PubMed
Summary
This summary is machine-generated.

True hermaphroditism, a rare disorder of sexual differentiation (DSD), presents unique challenges. This case highlights a 3-year-old with an undescended testis and hypospadias, revealing complex anatomical variations.

Keywords:
Disorders of sexual differentiationPersistent mullerian duct syndromeTrue hermaphrodite

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Last Updated: May 18, 2026

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Measuring Sperm Guidance and Motility within the Caenorhabditis elegans Hermaphrodite Reproductive Tract
10:07

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Published on: June 6, 2019

Area of Science:

  • Endocrinology
  • Pediatric Surgery
  • Genetics

Background:

  • True hermaphroditism is a rare disorder of sexual differentiation (DSD), accounting for only 5% of all DSD cases.
  • It involves the presence of both ovarian and testicular tissue in an individual.

Observation:

  • A 3-year-old child presented with a left undescended testis and penoscrotal hypospadias.
  • Previous chordee correction was performed 18 months prior.
  • Laparotomy revealed Mullerian structures on the left side and a normally descended right testis.

Findings:

  • The patient exhibited characteristics of true hermaphroditism, a rare DSD.
  • Surgical exploration confirmed the presence of internal Mullerian structures alongside gonadal tissue, indicating complex sexual differentiation.
  • Asymmetrical gonadal descent and associated anomalies were noted.

Implications:

  • This case underscores the importance of thorough diagnostic evaluation in DSD cases.
  • Early and accurate diagnosis is crucial for appropriate management and surgical planning.
  • Further research into the genetic and developmental pathways of DSD is warranted.