Related Experiment Video
Updated: May 18, 2026

Individualized Reconstitution of Human Milk Microbiota: A Feasible Approach in Real-World Settings
Published on: February 7, 2025
Human milk, a concrete risk for infection?
M Lanari1, P Sogno Valin, F Natale
1Paediatric Department, S. Maria della Scaletta General Hospital, Imola, Bologna, Italy. m.lanari@ausl.imola.bo.it
Breastfeeding offers significant health benefits for infants and mothers. Contraindications are rare, and risks of transmission during breastfeeding are usually outweighed by benefits, enabling informed decisions.
Area of Science:
- Public Health
- Infant Nutrition
- Maternal Health
Background:
- Breastfeeding is recommended as the standard for infant feeding up to six months and beyond.
- Numerous studies confirm improved infant and maternal health outcomes.
- Preterm infants particularly benefit from reduced risks of severe retinopathy of prematurity, sepsis, and necrotizing enterocolitis.
Purpose of the Study:
- To review contraindications for breastfeeding during maternal infections.
- To discuss transmission routes of pathogens from mother to infant during breastfeeding.
- To inform decision-making regarding infant feeding when maternal infection is present.
Main Methods:
- Literature review of studies on breastfeeding and maternal infections.
- Analysis of pathogen transmission routes (respiratory, direct contact, breast milk).
- Evaluation of risks versus benefits of breastfeeding in specific maternal infectious conditions.
Main Results:
- Breastfeeding is rarely contraindicated, even with maternal infections.
- Transmission can occur via respiratory secretions, direct contact with lesions, or breast milk.
- Exceptions include Human T-lymphotropic virus type I (HTLV-I) and Human Immunodeficiency Virus (HIV) in industrialized nations.
Conclusions:
- The theoretical risk of pathogen transmission via breast milk must be weighed against the benefits of breastfeeding.
- Mothers and parents can make informed decisions by discussing risks and benefits.
- Breastfeeding should be supported as a public health priority.
More Related Videos
08:12Isolation of Leukocytes from Human Breast Milk for Use in an Antibody-dependent Cellular Phagocytosis Assay of HIV Targets
Published on: September 6, 2019
13:00Intranasal Immunization and Milk Collection in Studies of Maternal Immunization in New Zealand White Rabbits (Oryctolagus cuniculus)
Published on: July 31, 2021
Related Concept Videos
Development of Human Microbiota
Development of Immunocompetence
The initial cells that migrate from the fetal thymus settle within the skin and epithelial tissues lining the mouth, digestive tract, and in females, the uterus and vagina. These cells, including skin-based dendritic cells, serve as antigen-presenting cells, playing a key role in T cell activation.
Subsequent T...
Development of the Oral Microbiota
Factors Affecting the Risk of Infection
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin create...
Surface Membrane Barriers
The outer layer of the skin, the epidermis, is a robust barrier comprising layers of closely packed keratinized cells. This dense arrangement prevents microbes from penetrating the body. The periodic shedding of epidermal cells...
Infection
The chain begins with pathogens: bacteria, viruses, fungi, prions, or parasites such as protozoa helminths. These can be present on the skin as transient or resident flora, or they can be acquired from the environment. Identifying and treating the type of infection and...