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Updated: May 18, 2026

Murine Oropharyngeal Aspiration Model of Ventilator-associated and Hospital-acquired Bacterial Pneumonia
Published on: June 28, 2018
Number needed to treat for subglottic secretion drainage technology as a ventilator-associated pneumonia prevention
Abstract:
The number needed to treat can be calculated for ventilator-associated pneumonia reduction strategies such as subglottic secretion drainage technology based on previous work establishing its relative risk reduction. Assuming an incidence of 4%, employing subglottic secretion drainage in 33 patients will prevent one case of ventilator-associated pneumonia, and thus potentially 4 cases annually in an average hospital in the United States. With a previously described limit of £300 ($470 USD) additional cost per 10 days of ventilation as a threshold of investment for technologies to reduce ventilator-associated pneumonia, subglottic secretion drainage technology is both clinically and cost effective.
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