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Published on: September 19, 2018
ABO blood groups and abdominal aortic aneurysm
Gertrud Viklander1, Jonas Wallinder, Anders E Henriksson
1Department of Laboratory Medicine, Sundsvall County Hospital, Sundsvall, Sweden.
Summary
This study found no link between ABO blood groups and abdominal aortic aneurysm (AAA) or its rupture. Blood type does not appear to be a risk factor for developing AAA.
Area of Science:
- Vascular Surgery
- Genetics
- Epidemiology
Background:
- Previous research suggested a link between non-O blood groups and atherosclerosis-related vascular diseases.
- Abdominal aortic aneurysm (AAA) is commonly considered a manifestation of atherosclerosis.
Purpose of the Study:
- To investigate the association between ABO blood groups and abdominal aortic aneurysm (AAA).
- To specifically examine if ABO blood groups correlate with AAA rupture.
Main Methods:
- A prospective study involving 504 patients who underwent surgery for AAA.
- Comparison of ABO blood group distributions between AAA patients and a population-based control group.
- Analysis of ABO blood group distribution in patients with ruptured versus non-ruptured AAA.
Main Results:
- The distribution of ABO blood groups in patients operated on for AAA was similar to the general population.
- No significant difference in ABO blood group distribution was observed between patients with ruptured AAA (n=174) and non-ruptured AAA (n=330).
Conclusions:
- This study did not find evidence supporting an association between ABO blood groups and the presence of abdominal aortic aneurysm.
- ABO blood groups do not appear to be a significant risk factor for AAA or its rupture.
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