Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Appendicitis-I: Introduction

Appendicitis-I: Introduction

The appendix, a small, narrow, blind tube extending from the inferior part of the cecum, is widely regarded as a vestigial organ, having lost much of its original function through evolution. Despite its diminished role, the appendix can become inflamed, a condition known as appendicitis.
Etiology: Appendicitis can arise from various causes, primarily rooted in the obstruction of the appendix lumen. Factors contributing to this obstruction include fecal accumulation, lymphoid hyperplasia and, in...

Appendicitis

Appendicitis

Appendicitis is an acute inflammatory condition of the vermiform appendix, most commonly caused by obstruction of its lumen. The appendix is a narrow, blind-ended pouch that extends from the cecum, making it particularly prone to obstruction. Causes include fecaliths, lymphoid hyperplasia (often after viral infections), parasites, tumors, or foreign bodies. This obstruction initiates a cascade of pathological changes.Luminal Obstruction and Early InflammationAfter obstruction, normal mucosal...

Appendicitis-II: Diagnostic Studies and Management

Appendicitis-II: Diagnostic Studies and Management

Diagnosing and managing appendicitis requires a structured and comprehensive approach that spans from initial assessment to postoperative care. Here is an overview of the process:
Diagnosing Appendicitis
It requires a multifaceted approach, starting with a detailed physical examination to pinpoint the location and nature of the pain and identify any associated symptoms. Laboratory tests play a crucial role. A complete Blood Count (CBC) typically reveals leukocytosis (an increased number of...

Intestinal Obstruction II: Pathophysiology

Intestinal Obstruction II: Pathophysiology

Intestinal obstruction triggers a series of physiological responses, starting with gas and fluid accumulation in the bowel segment proximal to the obstruction, leading to distension. This distended intestine compresses the diaphragm, hindering lung expansion and potentially leading to reduced respiratory effort, atelectasis, and pneumonia.To overcome the blockage, the gut intensifies contractions, causing colicky abdominal pain, nausea, and vomiting, which reduces fluid and food intake and...

Intestinal Obstruction I: Introduction

Intestinal Obstruction I: Introduction

Intestinal obstruction is a partial or complete blockage of the small or large intestine that disrupts the normal flow of intestinal contents through the lumen. This interruption impairs digestion, absorption, and fluid balance, and may lead to serious complications if not treated promptly.Mechanical ObstructionMechanical obstruction occurs when a physical blockage prevents intestinal contents from passing, arising from within the lumen or the bowel wall, or from external compression.Adhesions,...

Diverticular Disease of the Colon

Diverticular Disease of the Colon

Diverticular disease involves the formation of diverticula—small sac-like outpouchings of the colonic wall—and their complications. It most commonly affects the sigmoid colon due to higher intraluminal pressure and structural vulnerability. It results from structural weakness and increased pressure in the colon, producing pseudodiverticula that may remain silent or progress to inflammation and serious complications.Structure of DiverticulaIn diverticulosis, these outpouchings are...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Educational Effects of Training With a Virtual Reality-Based Objective Structured Clinical Examination Software.

Journal of medical education and curricular development·2026

Same author

Corrigendum to "Role of gonadal soma-derived growth factor (gsdf) on sex-differentiation in Nile tilapia, Oreochromis niloticus" [Gen. Comp. Endocrinol. 377 (2026) 114884].

General and comparative endocrinology·2026

Same author

Role of gonadal soma-derived growth factor (gsdf) on sex-differentiation in Nile tilapia, Oreochromis niloticus.

General and comparative endocrinology·2026

Same author

An ns-3 Evaluation Framework for Receiver-Initiated MAC Protocols with Configurable Enhancement Modules Across Various Network Scenarios.

Sensors (Basel, Switzerland)·2026

Same author

Precision Oncology for Pediatric Solid Tumors Using In-Hospital Pediatric/AYA Malignancy-Specific Panel Sequencing.

Cancer science·2025

Same author

Retrospective study of stage IV extracranial germ cell tumors: A report from the Japan Children's Cancer Group.

Pediatrics international : official journal of the Japan Pediatric Society·2025

Search research articles

Related Experiment Video

Updated: May 18, 2026

Extrahepatic Bile Duct and Gall Bladder Dissection in Nine-Day-Old Mouse Neonates

Extrahepatic Bile Duct and Gall Bladder Dissection in Nine-Day-Old Mouse Neonates

Published on: August 23, 2022

Neonatal appendicitis mimicking intestinal duplication: a case report.

Isamu Saeki¹, Takeshi Yamanouchi, Sakura Tanaka

¹Department of Pediatric Surgery, Fukuoka Children's Hospital and Medical Center for Infectious Diseases, 2-5-1 Tojin-machi Chuo-ku, Fukuoka, 810-0063, Japan. isamu@pedsurg.med.kyushu-u.ac.jp.

Journal of Medical Case Reports

|September 12, 2012

Summary

Neonatal appendicitis is rare but can mimic other conditions. A laparoscopic appendectomy in a 2-day-old infant successfully treated this condition, demonstrating a safe and effective approach.

More Related Videos

Microfluidic Model of Necrotizing Enterocolitis Incorporating Human Neonatal Intestinal Enteroids and a Dysbiotic Microbiome

Microfluidic Model of Necrotizing Enterocolitis Incorporating Human Neonatal Intestinal Enteroids and a Dysbiotic Microbiome

Published on: July 28, 2023

Related Experiment Videos

Last Updated: May 18, 2026

Extrahepatic Bile Duct and Gall Bladder Dissection in Nine-Day-Old Mouse Neonates

Extrahepatic Bile Duct and Gall Bladder Dissection in Nine-Day-Old Mouse Neonates

Published on: August 23, 2022

Microfluidic Model of Necrotizing Enterocolitis Incorporating Human Neonatal Intestinal Enteroids and a Dysbiotic Microbiome

Microfluidic Model of Necrotizing Enterocolitis Incorporating Human Neonatal Intestinal Enteroids and a Dysbiotic Microbiome

Published on: July 28, 2023

Area of Science:

Pediatric Surgery
Neonatal Medicine
Gastrointestinal Surgery

Background:

Acute appendicitis is a frequent diagnosis in older children.
Neonatal appendicitis is exceptionally rare, posing diagnostic challenges.

Purpose of the Study:

To report a case of neonatal appendicitis.
To highlight its potential to mimic intestinal duplication.
To evaluate the safety and efficacy of laparoscopic appendectomy in neonates.

Main Methods:

Case report of a 2-day-old neonate.
Diagnosis of neonatal appendicitis presenting as an abdominal mass.
Surgical intervention via laparoscopic appendectomy with adhesiolysis.

Main Results:

Successful laparoscopic appendectomy was performed.
The infant experienced an uneventful postoperative recovery.
The laparoscopic approach offered good cosmetic outcomes.

Conclusions:

Neonatal appendicitis can present atypically, mimicking conditions like intestinal duplication.
Laparoscopic appendectomy is a safe, effective, and cosmetically favorable treatment for neonatal appendicitis.