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Related Concept Videos

Classification of Epithelial Tissues: Simple Epithelium01:30

Classification of Epithelial Tissues: Simple Epithelium

Simple epithelium consists of a single layer of cells that lines body cavities and blood vessels. The shape of the cells in the epithelium reflects the function of the tissue. Cells in simple squamous epithelium appear as thin scales with flat, elliptical nuclei that mirror the form of the cell.
Because of the thinness of the cells, simple squamous epithelium is present where the rapid passage of chemical compounds is observed. For example, the endothelium that lines the capillaries and vessels...
Classification of Epithelial Tissues: Glandular Epithelium01:20

Classification of Epithelial Tissues: Glandular Epithelium

The glandular epithelium is made of one or more epithelial cells modified to synthesize and secrete chemical substances. Glandular epithelia can be classified based on cell number. Unicellular glands have individual secretory cells scattered across the epithelial monolayer. In contrast, multicellular glands consist of a hollow tubular duct attached to the cluster of secretory cells located in the deep pockets.
Multicellular glands are formed during early development when epithelial budding...
Tissue Membranes01:27

Tissue Membranes

A tissue membrane is a thin layer of cells that covers the outside of the body, the organs, internal passageways that lead to the exterior of the body, and the lining of the moveable joint cavities. There are two basic types of tissue membranes— connective tissue and epithelial membranes.
Connective Tissue Membranes
The connective tissue membrane is formed solely from connective tissue. These membranes encapsulate organs, such as the kidneys, and line our movable joints. A synovial membrane is...
Skin Diseases and Disorders01:23

Skin Diseases and Disorders

Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Skin Cancer01:30

Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Clinical Applications of Epidermal Stem Cells01:19

Clinical Applications of Epidermal Stem Cells

Epidermal stem cells (EpiSCs) are mainly located at the basal layer of the epidermis. These cells repair minor injuries of the skin and replace dead skin cells. However, EpiSCs’ cannot heal severe wounds such as major burns or those from diabetes or hereditary disorders. In such cases, culturing the epidermal stem cells from the patient is possible and has yielded successful treatment options, such as laboratory-grown skin grafts. These grafts are synthesized using a patient’s own EpiSCs...

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Related Experiment Video

Updated: May 18, 2026

Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia
06:15

Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia

Published on: August 9, 2024

Primary cutaneous adenomyoepithelioma.

Payam Saadat1, Brittney K De Clerck, Manjunath S Vadmal

  • 1Department of Dermatology, University of Southern California-Keck School of Medicine, Los Angeles, California, USA.

Annals of Clinical and Laboratory Science
|September 12, 2012
PubMed
Summary

Adenomyoepitheliomas are rare biphasic tumors. This report details a primary cutaneous adenomyoepithelioma case, offering insights into diagnosis and treatment.

Area of Science:

  • Oncology
  • Dermatopathology
  • Tumor Biology

Background:

  • Adenomyoepitheliomas are biphasic neoplasms with epithelial and myoepithelial cells.
  • These tumors typically occur in the breast, but rare instances are found in salivary glands, lungs, and vulva.
  • The molecular mechanisms, including the role of p27/kip-1 protein, are under investigation.

Observation:

  • Primary cutaneous adenomyoepithelioma is exceptionally rare, with only three previously documented cases.
  • This study presents a novel case of primary cutaneous adenomyoepithelioma.
  • The case underwent thorough histological and immunohistochemical analysis.

Findings:

  • Detailed characterization of the primary cutaneous adenomyoepithelioma.
  • Exploration of differential diagnoses for cutaneous biphasic tumors.

Related Experiment Videos

Last Updated: May 18, 2026

Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia
06:15

Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia

Published on: August 9, 2024

  • Analysis of the tumor's biological behavior and potential treatment strategies.

    • Implications:

    • Adds to the scarce literature on primary cutaneous adenomyoepitheliomas.
    • Provides valuable data for understanding and diagnosing this rare skin tumor.
    • Informs clinical management and treatment approaches for adenomyoepitheliomas.