Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Fractures: Bone Repair01:27

Fractures: Bone Repair

Treatment for a fracture is based on the type of break, the bone affected, and the patient's age.
Minor fractures with no bone displacement are treated by immobilizing the fractured bone using a cast or splint. However, in the case of fractures with displaced bones, the broken bones are repositioned before immobilization to ensure successful healing without deformation and loss of function. The realignment of fractured bone ends is performed through a process called reduction. If the procedure...
Healing II: Complications01:24

Healing II: Complications

Complications during healing arise when tissue repair is altered by local or systemic factors. These changes involve abnormal collagen deposition, altered biomechanics, and reduced vascular supply, impairing restoration of normal structure and function.Loss of FunctionScar tissue differs significantly from the original tissue it replaces. In the skin, fibrosis lacks adnexal structures such as hair follicles, sebaceous glands, and sweat glands. Their absence reduces tactile sensitivity, impairs...
Flail Chest-II01:26

Flail Chest-II

Managing flail chest, a condition characterized by a segment of the chest wall moving independently from the rest of the thoracic cage, requires a comprehensive approach. It includes a thorough assessment of the patient's condition, a diagnostic evaluation to determine the extent of the injury, and the implementation of appropriate medical interventions tailored to the individual's needs.
Assessment:
1. Clinical Evaluation:
History:

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Emergency Free Flap Reconstruction in Traumatic Extremity Injuries: Clinical Indications and Framework.

Microsurgery·2026
Same author

Targeted Muscle Reinnervation for Management and Prevention of Symptomatic Neuroma.

Muscle & nerve·2026
Same author

Algorithm for Surgical Management of Symptomatic Hand and Digital Neuromas.

Plastic and reconstructive surgery. Global open·2026
Same author

Pilot Study: DermiSphere: A Novel Hydrogel with Collagen Microspheres Dermal Regeneration Template.

Plastic and reconstructive surgery. Global open·2026
Same author

Building a behavioral health crisis response program: a qualitative implementation case study.

Health affairs scholar·2026
Same author

"Painless palsy" revisited: a systematic review of pain in hereditary neuropathy with liability to pressure palsies.

Pain management·2026

Related Experiment Video

Updated: May 18, 2026

Quantification of Strain in a Porcine Model of Skin Expansion Using Multi-View Stereo and Isogeometric Kinematics
14:14

Quantification of Strain in a Porcine Model of Skin Expansion Using Multi-View Stereo and Isogeometric Kinematics

Published on: April 16, 2017

Soft tissue injury management with a continuous external tissue expander.

Gabriel F Santiago1, Benjamin Bograd, Patrick L Basile

  • 1Walter Reed National Military Medical Center, Bethesda, MD 20889, USA.

Annals of Plastic Surgery
|September 12, 2012
PubMed
Summary

Continuous external tissue expansion effectively manages blast-related extremity soft tissue defects, aiding in wound closure with reduced morbidity. This method significantly decreases wound size, facilitating delayed primary closure and minimizing complex reconstructive procedures.

More Related Videos

A Mouse Distraction Osteogenesis Model
04:24

A Mouse Distraction Osteogenesis Model

Published on: November 14, 2018

Related Experiment Videos

Last Updated: May 18, 2026

Quantification of Strain in a Porcine Model of Skin Expansion Using Multi-View Stereo and Isogeometric Kinematics
14:14

Quantification of Strain in a Porcine Model of Skin Expansion Using Multi-View Stereo and Isogeometric Kinematics

Published on: April 16, 2017

A Mouse Distraction Osteogenesis Model
04:24

A Mouse Distraction Osteogenesis Model

Published on: November 14, 2018

Area of Science:

  • Reconstructive Surgery
  • Trauma Surgery
  • Tissue Engineering

Background:

  • Blast exposure commonly causes severe soft tissue injuries, particularly to extremities, often with associated orthopedic and nerve damage.
  • Management of these massive defects necessitates advanced reconstructive techniques for definitive wound coverage.
  • Continuous external tissue expansion is utilized to reduce wound burden and achieve closure in blast-injured patients.

Purpose of the Study:

  • To evaluate the efficacy of a continuous external tissue expansion system (DermaClose RC) in treating massive extremity soft tissue injuries.
  • To determine the time to definitive wound closure and the methods employed.
  • To prospectively analyze wound surface area reduction and complications in a subset of patients.

Main Methods:

  • An early series of 14 patients with massive extremity soft tissue injuries treated with the DermaClose RC system was reviewed.
  • Outcome measures included time to definitive closure and closure method.
  • A 5-patient subgroup underwent prospective analysis of initial wound surface area, percentage reduction, and complications.

Main Results:

  • Mean time to wound coverage was 4.4 days (range 1-6 days).
  • Delayed primary closure was achieved in 85.7% of patients; 2 required split thickness skin grafting.
  • In the prospective subgroup, mean wound size decreased by 74.3% (range 44%-93%).

Conclusions:

  • Continuous external tissue expansion is a valuable adjunct for definitive wound closure in large, complex wounds.
  • The technique facilitates delayed primary closure, has low morbidity, and can reduce the need for more complex reconstructions.
  • An algorithm for utilizing continuous external tissue expansion is proposed to optimize wound closure and minimize donor-site morbidity.