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Panax ginseng in randomised controlled trials: a systematic review
Johannah L Shergis1, Anthony L Zhang, Wenyu Zhou
1Traditional and Complementary Medicine Research Program, School of Health Sciences and Health Innovations Research Institute-HIRi, RMIT University, Bundoora, Melbourne, Victoria, Australia.
Phytotherapy Research : PTR
|September 13, 2012
Summary
Panax ginseng shows potential for improving glucose metabolism and immune response. Further research is needed to confirm its effectiveness for conditions like type 2 diabetes and respiratory issues.
Area of Science:
- Herbal Medicine
- Pharmacology
- Systematic Review
Background:
- Panax ginseng is a widely used herb with claimed health benefits.
- Conclusive evidence for its therapeutic efficacy in specific diseases is lacking.
- Randomized controlled trials (RCTs) are crucial for evaluating herbal medicine efficacy.
Purpose of the Study:
- To systematically review RCTs evaluating the effects of Panax ginseng.
- To assess the quality of included studies and reported adverse events.
- To identify potential therapeutic applications of Panax ginseng.
Main Methods:
- Systematic literature search of four English databases without date restrictions.
- Inclusion of studies on Panax ginseng in diseased or healthy individuals.
- Quality assessment using the Cochrane risk of bias tool.
Main Results:
- 65 out of 475 studies met inclusion criteria, examining diverse health outcomes.
- Panax ginseng demonstrated promising effects on glucose metabolism and immune modulation.
- Most studies had unclear risk of bias; 135 minor adverse events were reported, with no serious events.
Conclusions:
- Panax ginseng may offer benefits for glucose metabolism and immune response.
- Potential implications exist for type 2 diabetes and chronic respiratory conditions.
- Further high-quality research is necessary to validate Panax ginseng's therapeutic potential.
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