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Evaluation of Colorectal Cancer Risk and Prevalence by Stool DNA Integrity Detection
Published on: June 8, 2020
Results of National Colorectal Cancer Screening Program in Croatia (2007-2011)
Miroslava Katičić1, Nataša Antoljak, Milan Kujundžić
1Miroslava Katičić, Department of Gastroenterology, Merkur University Hospital, 10000 Zagreb, Croatia. mkaticic@mef.hr
World Journal of Gastroenterology
|September 13, 2012
Summary
The Croatian National Colorectal Cancer Screening Program found 6.9% of participants tested positive for fecal occult blood, with 5.5% of those undergoing colonoscopy diagnosed with colorectal cancer or polyps. Increased participation is needed.
Area of Science:
- Public Health
- Gastroenterology
- Oncology
Background:
- Colorectal cancer (CRC) is a significant cause of cancer mortality in Croatia.
- The Croatian National CRC Screening Program was implemented in 2007 to address this issue.
- The program utilizes fecal occult blood testing (FOBT) followed by colonoscopy for positive cases.
Purpose of the Study:
- To evaluate the uptake and colonoscopic findings of the Croatian National Colorectal Cancer Screening Program.
- To analyze epidemiologic indicators related to CRC screening participation and outcomes.
Main Methods:
- A descriptive analysis of data from the Croatian National CRC Screening Program (2007-2011).
- Fecal occult blood testing (FOBT) offered to individuals aged 50-74.
- Colonoscopy performed for all FOBT-positive cases.
Main Results:
- 1,056,694 individuals were invited; 19.9% returned questionnaires, 181,102 submitted stool specimens.
- 6.9% of FOBT tests were positive, within expected European Union (EU) guidelines.
- Colonoscopy uptake was 66%, identifying CRC in 5.5% of cases and polyps in 39%.
Conclusions:
- The program identified a significant number of colorectal cancers and polyps.
- The FOBT positivity rate and colonoscopy findings align with EU guidelines.
- There is a need for improved awareness and participation in CRC screening through organizational and educational interventions.
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